oprk1 Protein, opioid receptor, kappa 1


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Official Full Name opioid receptor, kappa 1
Background The κ-opioid receptor (KOR) is a protein that in humans is encoded by the OPRK1 gene. The κ-opioid receptor is one of five related receptors that bind opium-like compounds in the brain and are responsible for mediating the effects of these compounds. These effects include altering the perception of pain, consciousness, motor control, and mood.
Synonyms OPRK1; K-OR-1; Kappa type opioid receptor; Kappa-type opioid receptor; KOR 1; KOR; KOR-1; Opiate receptor kappa 1; OPRK 1; OPRK; OPRK_HUMAN; Oprk2; R21; opioid receptor, kappa 1; OTTHUMP00000226313; Opioid Receptor, kappa; OTTHUMP00000226316; kappa opioid receptor; Opiate receptor, kappa-1
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human OPRK1-28446TH Recombinant Human OPRK1 Wheat Germ N/A
    Mouse OPRK1-12174M Recombinant Mouse OPRK1 Protein Mammalian Cell His
    Rat OPRK1-4194R Recombinant Rat OPRK1 Protein Mammalian Cell His
    Zebrafish OPRK1-9675Z Recombinant Zebrafish OPRK1 Mammalian Cell His
    Kit-0897 TR-FRET TR alpha Coactivator Assay Kit, goat N/A
    Kit-1066 Uric Acid Colorimetric/Fluorometric Assay Kit N/A
    Kit-1453 cAMP OPRK1 CHO-K1 GPCR Assay Kit N/A
    Kit-1454 OPRK1 U2OS β-Arrestin GPCR Assay Kit N/A
    Kit-1455 OPRK1 Total GPCR Internalization Assay Kit N/A

    oprk1 involved in several pathways and played different roles in them. We selected most pathways oprk1 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with oprk1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Neuroactive ligand-receptor interaction GABBR2; HRH2; DRD4B; TSPO; GRM7; GRIA1A; TAAR64; CHRNA4; TAAR8C; RXFP1

    oprk1 has several biochemical functions, for example, dynorphin receptor activity, neuropeptide binding, opioid receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by oprk1 itself. We selected most functions oprk1 had, and list some proteins which have the same functions with oprk1. You can find most of the proteins on our site.

    Function Related Protein
    dynorphin receptor activity OPRK1
    neuropeptide binding MC3R; SSTR2; ADCYAP1R1; GALR1; GPR149; GPR1; OPRM1; PTGDR2; MC4R; NPY8BR
    opioid receptor activity OPRK1; NPBWR1; SIGMAR1; OPRD1A; OGFR; OPRD1B; NPBWR2; OPRD1
    protein binding IRS2; KRTAP9-4; BORA; VDAC1; ARL6IP4; CRY1; LZTS1; CPT1B; DOCK2; ALG2

    oprk1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with oprk1 here. Most of them are supplied by our site. Hope this information will be useful for your research of oprk1.


    Faisal, M; Waseem, D; et al. A molecular prospective provides new insights into implication of PDYN and OPRK1 genes in alcohol dependence. COMPUTERS IN BIOLOGY AND MEDICINE 53:250-257(2014).
    Trescot, AM; Faynboym, S; et al. A Review of the Role of Genetic Testing in Pain Medicine. PAIN PHYSICIAN 17:425-445(2014).

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