P2RY2
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Official Full Name
purinergic receptor P2Y, G-protein coupled, 2
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Background
P2Y purinoceptor 2 is a protein that in humans is encoded by the P2RY2 gene. The product of this gene, P2Y2 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to both adenosine and uridine nucleotides. It may participate in control of the cell cycle of endometrial carcinoma cells. Three transcript variants encoding the same protein have been identified for this gene. -
Synonyms
purinergic receptor P2Y, G-protein coupled, 2; P2U; HP2U; P2U1; P2UR; P2Y2; P2RU1; P2Y2R; P2Y purinoceptor 2; ATP receptor; P2U purinoceptor 1; P2U nucleotide receptor; purinergic receptor P2Y2; OTTHUMP00000237494; OTTHUMP00000237495; OTTHUMP00000237496; MGC20088; purinoceptor P2Y2; MGC40010; Purinergic receptor;
- Involved Pathway
- Protein Function
- Interacting Protein
P2RY2 involved in several pathways and played different roles in them. We selected most pathways P2RY2 participated on our site, such as Neuroactive ligand-receptor interaction, Inflammatory mediator regulation of TRP channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with P2RY2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuroactive ligand-receptor interaction | CCKAR;TAAR12B;HTR1AB;PRLHR;CNR1;HCRTR2;SSTR4;NPY5R;BDKRB2 |
| Inflammatory mediator regulation of TRP channels | TRPV2;CYP2C38;CYP2C37;ACCN3;CALML5;CYP2C39;ASIC3;HTR2C;GNAQ |
P2RY2 has several biochemical functions, for example, ATP binding, G-protein coupled purinergic nucleotide receptor activity, UTP-activated nucleotide receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by P2RY2 itself. We selected most functions P2RY2 had, and list some proteins which have the same functions with P2RY2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | DDX4;CARNS1;TTBK1;HSP90AB1;TOP2A;HSPA12A;ACOT12;UBE2H;CMPK2 |
| G-protein coupled purinergic nucleotide receptor activity | GPR34B;P2RY13;P2RY14;P2RY10;P2RY2;P2RY1;P2RY6;PTAFR;P2RY8 |
| UTP-activated nucleotide receptor activity | P2RY2;P2RY4 |
| receptor activity | ITGB1B.2;ITGB3B;ADIPOR2;CHRM3;IL10RA;VPREB1;CSF2RA;MRC1;AGER |
P2RY2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with P2RY2 here. Most of them are supplied by our site. Hope this information will be useful for your research of P2RY2.
SLC9A3R1
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