P2RY2

  • Official Full Name

    purinergic receptor P2Y, G-protein coupled, 2

  • Overview

    P2Y purinoceptor 2 is a protein that in humans is encoded by the P2RY2 gene. The product of this gene, P2Y2 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to both adenosine and uridine nucleotides. It may participate in control of the cell cycle of endometrial carcinoma cells. Three transcript variants encoding the same protein have been identified for this gene.
  • Synonyms

    purinergic receptor P2Y, G-protein coupled, 2; P2U; HP2U; P2U1; P2UR; P2Y2; P2RU1; P2Y2R; P2Y purinoceptor 2; ATP receptor; P2U purinoceptor 1; P2U nucleotide receptor; purinergic receptor P2Y2; OTTHUMP00000237494; OTTHUMP00000237495; OTTHUMP00000237496; MGC20088; purinoceptor P2Y2; MGC40010; Purinergic receptor;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Sus scrofa (Pig)
  • E.coli
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human P2RY2-1498H Recombinant Human P2RY2, GST-tagged E.coli GST
Human P2RY2-3486HCL Recombinant Human P2RY2 293 Cell Lysate HEK293 N/A
Human P2RY2-3487HCL Recombinant Human P2RY2 293 Cell Lysate HEK293 N/A
Human P2RY2-2540H Recombinant Human P2RY2 Protein, His-tagged E.coli N-His
Mouse P2RY2-12277M Recombinant Mouse P2RY2 Protein Mammalian Cell His
Mouse P2RY2-6460M Recombinant Mouse P2RY2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse P2ry2-1891M Recombinant Mouse P2ry2 Protein, His-tagged E.coli N-His
Mouse P2RY2-6460M-B Recombinant Mouse P2RY2 Protein Pre-coupled Magnetic Beads HEK293
Rat P2RY2-4237R Recombinant Rat P2RY2 Protein Mammalian Cell His
Rat P2RY2-3899R Recombinant Rat P2RY2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat P2RY2-3899R-B Recombinant Rat P2RY2 Protein Pre-coupled Magnetic Beads HEK293
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) RFL19448CF Recombinant Full Length Cricetulus Griseus P2Y Purinoceptor 2(P2Ry2) Protein, His-Tagged E.coli expression system His
Homo sapiens (Human) RFL34176HF Recombinant Full Length Human P2Y Purinoceptor 2(P2Ry2) Protein, His-Tagged E.coli expression system His
Mus musculus (Mouse) RFL32844MF Recombinant Full Length Mouse P2Y Purinoceptor 2(P2Ry2) Protein, His-Tagged E.coli expression system His
Rattus norvegicus (Rat) RFL4995RF Recombinant Full Length Rat P2Y Purinoceptor 2(P2Ry2) Protein, His-Tagged E.coli expression system His
Sus scrofa (Pig) RFL29094SF Recombinant Full Length Pig P2Y Purinoceptor 2(P2Ry2) Protein, His-Tagged E.coli expression system His
Kit-1472 P2RY2 U2OS1 β-Arrestin GPCR Assay Kit N/A
Kit-0984 Fluorimetric Hydrogen Peroxide Assay Kit (Red) N/A
Kit-1471 P2RY2 Activated GPCR Internalization Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein

P2RY2 involved in several pathways and played different roles in them. We selected most pathways P2RY2 participated on our site, such as Neuroactive ligand-receptor interaction, Inflammatory mediator regulation of TRP channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with P2RY2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neuroactive ligand-receptor interactionAGTR2;P2RX8;PTGER4C;APLNR;S1PR2;RXFP2A;P2RY14;MCHR1;RXFP1
Inflammatory mediator regulation of TRP channelsHTR2B;ALOX12E;PRKCE;PRKCH;CYP4A12A;CALML5;CYP2C54;CALM4;PPP1CB

P2RY2 has several biochemical functions, for example, ATP binding, G-protein coupled purinergic nucleotide receptor activity, UTP-activated nucleotide receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by P2RY2 itself. We selected most functions P2RY2 had, and list some proteins which have the same functions with P2RY2. You can find most of the proteins on our site.

Function Related Protein
ATP bindingPI4KA;DDX19;CKMT1A;PIP4K2A;P2RX7;HSPA9;BMX;PSKH1;PDXK
G-protein coupled purinergic nucleotide receptor activityP2RY1;GPR171;PTAFR;P2RY11;GPR34B;P2RY14;P2RY10;P2RY13;P2RY2
UTP-activated nucleotide receptor activityP2RY2;P2RY4
receptor activityANXA2R;TLR6;RRBP1B;NLGN3;ERBB3B;ANTXRL;LILRB4;SEMA4D;TLR1

P2RY2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with P2RY2 here. Most of them are supplied by our site. Hope this information will be useful for your research of P2RY2.

SLC9A3R1

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