P2RY6

  • Official Full Name

    pyrimidinergic receptor P2Y, G-protein coupled, 6

  • Overview

    The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. Four transcript variants encoding the same isoform have been identified for this gene.
  • Synonyms

    P2RY6; pyrimidinergic receptor P2Y, G-protein coupled, 6; P2Y purinoceptor 6; P2Y6; G coupled nucleotide receptor; G protein coupled 6; MGC15335; P2 purinoceptor; P2RY6_HUMAN; P2Y6 receptor; PP2891; Purinergic receptor P2Y6; pyrimidinergic receptor P2Y; OTTHUMP00000237497; OTTHUMP00000237500; OTTHUMP00000237501; OTTHUMP00000237502; OTTHUMP00000237504; OTTHUMP00000237505; OTTHUMP00000237506; G-coupled nucleotide receptor;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human P2RY6-30535TH Recombinant Human P2RY6 Wheat Germ N/A 102 amino acids
Human P2RY6-3484HCL Recombinant Human P2RY6 293 Cell Lysate HEK293 N/A
Human P2RY6-3485HCL Recombinant Human P2RY6 293 Cell Lysate HEK293 N/A
Rat P2RY6-4239R Recombinant Rat P2RY6 Protein Mammalian Cell His
Rat P2RY6-3901R-B Recombinant Rat P2RY6 Protein Pre-coupled Magnetic Beads HEK293
Rat P2RY6-3901R Recombinant Rat P2RY6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Homo sapiens (Human) RFL25172HF Recombinant Full Length Human P2Y Purinoceptor 6(P2Ry6) Protein, His-Tagged E.coli expression system His Full Length (1-328)
Mus musculus (Mouse) RFL23927MF Recombinant Full Length Mouse P2Y Purinoceptor 6(P2Ry6) Protein, His-Tagged E.coli expression system His Full Length (1-328)
Rattus norvegicus (Rat) RFL19532RF Recombinant Full Length Rat P2Y Purinoceptor 6(P2Ry6) Protein, His-Tagged E.coli expression system His Full Length (1-328)
Chicken P2RY6-6749C Recombinant Chicken P2RY6 Mammalian Cell His
Kit-0967 TR-FRET RAR beta Coactivator Assay Kit, goat N/A
Kit-1475 P2RY6 CHO-K1 β-Arrestin GPCR Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

P2RY6 involved in several pathways and played different roles in them. We selected most pathways P2RY6 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with P2RY6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neuroactive ligand-receptor interactionPTGER1B;GALR1;TSPO;NPY8BR;S1PR4;LPAR2;GHSRA;PRLR;S1PR5A

P2RY6 has several biochemical functions, for example, G-protein coupled purinergic nucleotide receptor activity, G-protein coupled receptor activity, UDP-activated nucleotide receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by P2RY6 itself. We selected most functions P2RY6 had, and list some proteins which have the same functions with P2RY6. You can find most of the proteins on our site.

Function Related Protein
G-protein coupled purinergic nucleotide receptor activityGPR171;P2RY1;P2RY13;PTAFR;P2RY11;P2RY8;P2RY14;P2RY6;P2RY2
G-protein coupled receptor activityTAAR14G;COR6;OLFCS2;TAAR14E;OR115-6;OPN4A;GRM5;OLFCG2;GHSR
UDP-activated nucleotide receptor activityP2RY6;P2RY14
protein bindingROCK2A;ITGA2;PTK7;C2orf57;MMACHC;ACTN3;COMMD7;COMT;NUBP1

P2RY6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with P2RY6 here. Most of them are supplied by our site. Hope this information will be useful for your research of P2RY6.

PLSCR1; KRTAP10-7

Gene Family

GPCRs

Research Area

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