P2RY6
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Official Full Name
pyrimidinergic receptor P2Y, G-protein coupled, 6
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Overview
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. Four transcript variants encoding the same isoform have been identified for this gene. -
Synonyms
P2RY6; pyrimidinergic receptor P2Y, G-protein coupled, 6; P2Y purinoceptor 6; P2Y6; G coupled nucleotide receptor; G protein coupled 6; MGC15335; P2 purinoceptor; P2RY6_HUMAN; P2Y6 receptor; PP2891; Purinergic receptor P2Y6; pyrimidinergic receptor P2Y; OTTHUMP00000237497; OTTHUMP00000237500; OTTHUMP00000237501; OTTHUMP00000237502; OTTHUMP00000237504; OTTHUMP00000237505; OTTHUMP00000237506; G-coupled nucleotide receptor;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Assay Kits
- Chicken
- Homo sapiens (Human)
- Human
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- E.coli expression system
- HEK293
- Mammalian Cell
- Wheat Germ
- His
- Fc
- Avi
- Non
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | P2RY6-30535TH | Recombinant Human P2RY6 | Wheat Germ | Non | 102 amino acids |
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| Human | P2RY6-3484HCL | Recombinant Human P2RY6 293 Cell Lysate | HEK293 | Non |
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| Human | P2RY6-3485HCL | Recombinant Human P2RY6 293 Cell Lysate | HEK293 | Non |
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| Rat | P2RY6-4239R | Recombinant Rat P2RY6 Protein | Mammalian Cell | His |
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| Rat | P2RY6-3901R-B | Recombinant Rat P2RY6 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | P2RY6-3901R | Recombinant Rat P2RY6 Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi |
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| Homo sapiens (Human) | RFL25172HF | Recombinant Full Length Human P2Y Purinoceptor 6(P2Ry6) Protein, His-Tagged | E.coli expression system | His | Full Length (1-328) |
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| Mus musculus (Mouse) | RFL23927MF | Recombinant Full Length Mouse P2Y Purinoceptor 6(P2Ry6) Protein, His-Tagged | E.coli expression system | His | Full Length (1-328) |
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| Rattus norvegicus (Rat) | RFL19532RF | Recombinant Full Length Rat P2Y Purinoceptor 6(P2Ry6) Protein, His-Tagged | E.coli expression system | His | Full Length (1-328) |
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| Chicken | P2RY6-6749C | Recombinant Chicken P2RY6 | Mammalian Cell | His |
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| Kit-0967 | TR-FRET RAR beta Coactivator Assay Kit, goat | Non |
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| Kit-1475 | P2RY6 CHO-K1 β-Arrestin GPCR Assay Kit | Non |
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- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
P2RY6 involved in several pathways and played different roles in them. We selected most pathways P2RY6 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with P2RY6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuroactive ligand-receptor interaction | CCKBR;CYSLTR2;GRM5;GRIN2BB;CALCR;TAAR10A;DRD4B;CHRM5A;PTGER1B |
P2RY6 has several biochemical functions, for example, G-protein coupled purinergic nucleotide receptor activity, G-protein coupled receptor activity, UDP-activated nucleotide receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by P2RY6 itself. We selected most functions P2RY6 had, and list some proteins which have the same functions with P2RY6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein coupled purinergic nucleotide receptor activity | P2RY14;P2RY11;GPR171;GPR34B;P2RY13;P2RY2;P2RY10;P2RY6;P2RY8 |
| G-protein coupled receptor activity | TAAR8A;TAS2R200.2;OLFR469;FZD7A;OLFR477;GPR81;ADRB3B;OR6K3;GRM5 |
| UDP-activated nucleotide receptor activity | P2RY6;P2RY14 |
| protein binding | BATF3;CEP120;UBE2V1;SOX5;NRAP;HJURP;CCL4;ADRBK1;RAB14 |
P2RY6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with P2RY6 here. Most of them are supplied by our site. Hope this information will be useful for your research of P2RY6.
PLSCR1; KRTAP10-7
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