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PABPC4

  • Official Full Name

    poly(A) binding protein, cytoplasmic 4 (inducible form)

  • Overview

    PolyA-binding protein (PABP) is a ubiquitous RNA binding protein that contains 4 RNA recognition motifs and a proline-rich C-terminal domain responsible for protein-protein interaction. It is an important regulator of mRNA stability and translation. PABPC
  • Synonyms

    PABPC4; poly(A) binding protein, cytoplasmic 4 (inducible form); polyadenylate-binding protein 4; APP 1; iPABP; PABP-4; poly(A)-binding protein 4; activated-platelet protein 1; inducible poly(A)-binding protein; APP1; APP-1; PABP4; FLJ43938;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PABPC4-1504H Recombinant Human PABPC4 protein, His-tagged E.coli His 285-631 aa
Human PABPC4-1271HCL Recombinant Human PABPC4 cell lysate N/A
Human PABPC4-4390H Recombinant Human PABPC4 protein E.coli N/A 1-644aa
Zebrafish PABPC4-11444Z Recombinant Zebrafish PABPC4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PABPC4 involved in several pathways and played different roles in them. We selected most pathways PABPC4 participated on our site, such as RNA transport, mRNA surveillance pathway, RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with PABPC4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RNA transportPOP4;EIF4A1A;NUP205;NUP210L;EIF1;NXF2;SRRM1;UPF1;CLNS1A
mRNA surveillance pathwayEIF4A3;PAPOLB;PPP2R1B;ETF1A;SMG5;MSI1;PPP2R2A;NCBP2;HBS1L
RNA degradationCNOT6;PARN;DCP1B;CNOT1;SKIV2L;EXOSC10;PABPC4;ENO2;PABPC1B

PABPC4 has several biochemical functions, for example, nucleotide binding, poly(A) RNA binding, poly(A) binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PABPC4 itself. We selected most functions PABPC4 had, and list some proteins which have the same functions with PABPC4. You can find most of the proteins on our site.

Function Related Protein
nucleotide bindingGNAIA;NAIP7;MYO15;RBM27;SMYHC2;FLJ11011L;RBFOX1;ABCG2B;JAK2B
poly(A) RNA bindingCTNNA1;PPIB;SRP54A;MRPL40;RPL27A;ZC3H7A;SF1;PIN4;SNRNP200
poly(A) bindingTIA1;ZC3H14;SYNCRIP;DDX3X;PABPC1;PABPC3;PABPC4;EIF4A3;KHDRBS1
NOT poly(C) RNA binding
poly(U) RNA bindingMSI1;RBM11;KHDC1A;PNPT1;HNRNPH1;PABPC4;KHDRBS1;PATL2;MSI2
protein bindingGALT;MED23;TRIM54;CPSF6;ITGA4;CCL28;KRTAP4-11;CLSTN2;KLF17

PABPC4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PABPC4 here. Most of them are supplied by our site. Hope this information will be useful for your research of PABPC4.

YWHAZ; PHLDA1; SRPK2; PPM1B; HNF4A; ARF6; IKBKE; Klc1; PINX1; TNFRSF10D; PUF60; SMAD9; XRN1; 15-deoxy-delta(12,14; midostaurin; NS1

  • Q&As
  • Reviews

Q&As (7)

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How does PABPC4 interact with other RNA-binding proteins? 07/29/2020

PABPC4 works in conjunction with other RNA-binding proteins to coordinate mRNA regulation and translation.

What role does PABPC4 play in protein synthesis? 07/28/2020

PABPC4 plays a significant role in facilitating protein synthesis by stabilizing mRNA during translation.

What is the primary role of PABPC4 in mRNA regulation? 06/27/2018

PABPC4, a poly(A) binding protein, is crucial for regulating mRNA stability and translation in cells.

How do genetic variations in PABPC4 affect gene expression? 05/24/2018

Genetic mutations in PABPC4 can lead to disrupted mRNA processing and altered gene expression.

What is the impact of altered PABPC4 activity on cellular processes? 11/03/2017

Altered PABPC4 activity can impact various cellular functions, including protein production and cell signaling.

How does PABPC4 contribute to mRNA stability? 06/05/2017

It enhances mRNA stability by binding to the poly(A) tail, protecting mRNA from degradation.

What potential therapeutic applications arise from targeting PABPC4 in RNA-related disorders? 05/05/2017

Targeting PABPC4 could provide new treatment strategies for diseases involving mRNA processing abnormalities.

Customer Reviews (3)

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Reviews
07/10/2019

    Dependable partner, a cornerstone of our research.

    12/12/2018

      Efficient and precise, supports our research endeavors.

      08/11/2017

        Key to our research success, highly recommended.

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