PCNT
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Official Full Name
pericentrin
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Overview
The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM). The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. -
Synonyms
PCNT; pericentrin; PCNT2, pericentrin 2 (kendrin); KEN; kendrin; KIAA0402; PCN; PCNTB; SCKL4; Seckel syndrome 4; pericentrin B; pericentrin-2; pericentrin-B; pericentrin-380; MOPD2; PCNT2; PCTN2;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | PCNT-8024H | Recombinant Human PCNT protein, His & T7-tagged | E.coli | His/T7 | Arg2987~Thr3246 (Accession # O95613) |
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| Mouse | Pcnt-3322M | Recombinant Mouse Pcnt protein, His&Myc-tagged | E.coli | His&Myc | 2545-2810aa |
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| Mouse | Pcnt-1928M | Recombinant Mouse Pcnt Protein, His-tagged | E.coli | N-His | Leu2545-Pro2810 |
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PCNT involved in several pathways and played different roles in them. We selected most pathways PCNT participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PCNT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
PCNT has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by PCNT itself. We selected most functions PCNT had, and list some proteins which have the same functions with PCNT. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
PCNT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PCNT here. Most of them are supplied by our site. Hope this information will be useful for your research of PCNT.
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