PDE3B

  • Official Full Name

    PDE3B phosphodiesterase 3B, cGMP-inhibited

  • Overview

    Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3, 5monophosphate (cAMP and cGMP). Thus, these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling. The PDE3 enzyme belongs to a family of PDEs known as cGMPinhibited PDEs. The enzymes bind both cGMP and cAMP with different affinities. The PDE3 family is comprised of two genes, PDE3A and PDE3B
  • Synonyms

    PDE3B; phosphodiesterase 3B, cGMP-inhibited; cGMP-inhibited 3,5-cyclic phosphodiesterase B; HcGIP1; CGIP1; CGI-PDE B; cyclic nucleotide phosphodiesterase; cyclic GMP-inhibited phosphodiesterase B; cGIPDE1;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Sf9 Insect Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PDE3B-1526H Active Recombinant Human PDE3B, GST-tagged Sf9 Insect Cell GST 654 aa-end
Human PDE3B-474H Recombinant Human PDE3B, GST-tagged, Active Sf9 Insect Cell GST
Human PDE3B-29932TH Recombinant Human PDE3B N/A
Human PDE3B-742H Recombinant Human PDE3B Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human PDE3B-6370H Recombinant Human PDE3B Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PDE3B-3492H Recombinant Human PDE3B protein, His-tagged E.coli His 321-670 aa
Mouse Pde3b-4744M Recombinant Mouse Pde3b Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat PDE3B-4329R Recombinant Rat PDE3B Protein Mammalian Cell His
Rat PDE3B-3989R-B Recombinant Rat PDE3B Protein Pre-coupled Magnetic Beads HEK293
Rat PDE3B-3989R Recombinant Rat PDE3B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken PDE3B-2849C Recombinant Chicken PDE3B Mammalian Cell His
Kit-1837 PDE3B Assay Kit II N/A
Kit-1836 PDE3B Assay Kit I N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PDE3B involved in several pathways and played different roles in them. We selected most pathways PDE3B participated on our site, such as Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDE3B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Purine metabolismGUCY2C;POLR1C;ENTPD8;POLE;POLR2EB;POLR2C;NME5;NT5C2B;POLR2B
cGMP-PKG signaling pathwayATF4;NFATC2;MYLK;PIK3CD;PLCB4;ATP2A3;PIK3CG;NPPB;SLC8A1
cAMP signaling pathwayPAK1;PIK3CB;RAP1B;CAMK2A;ROCK2;CALM1;CNGA1;FSHR;AKT2
Insulin signaling pathwayPRKAR1B;NRAS;MKNK2A;RAF1A;EIF4E1C;INPP5K;CALM3B;RPS6KB2;PDPK1
Progesterone-mediated oocyte maturationAKT3A;ANAPC13;PRKACAB;MAD2L1;PIK3CB;HSP90AA1.1;PIK3R2;RAF1B;CDC26
Regulation of lipolysis in adipocytesIRS1;GNAI2;GNAS;PRKG2;PIK3R5;PRKACG;PLIN1;INSR;ABHD5
Renin secretionPPP3CA;PDE3B;PDE1A;ORAI1;AGTR1B;PTGER2;PPP3R1;GNAI1;CLCA1

PDE3B has several biochemical functions, for example, 3,5-cyclic-nucleotide phosphodiesterase activity, cGMP-inhibited cyclic-nucleotide phosphodiesterase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDE3B itself. We selected most functions PDE3B had, and list some proteins which have the same functions with PDE3B. You can find most of the proteins on our site.

Function Related Protein
3,5-cyclic-nucleotide phosphodiesterase activityPDE10A;PDE5A;PDE8A;PDE9A;PDE11A;PDE4D;PDE8B;PDE6D;PDE5AB
cGMP-inhibited cyclic-nucleotide phosphodiesterase activityPDE3A;USB1;PDE3B;TDP2B
metal ion bindingPXDN;ZNHIT2;ZHX2;ARL3;ACVR1;ADAMTS12;GNA11;YBEY;CDK15
protein bindingLIMS1;PMM2;OPRM1;CTAG1A;ZHX2;RNF111;CCNB1IP1;NFE2L2;PSMA7
protein kinase B bindingCCDC88A;PDE3B;RARA;TRAF6;ANKRD2;APPL1;PINK1;BCL10;BAD

PDE3B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDE3B here. Most of them are supplied by our site. Hope this information will be useful for your research of PDE3B.

RAPGEF3; PIK3R6; PIK3CG

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All PDE3B Products

Required fields are marked with *

My Review for All PDE3B Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends