PDE6D
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Official Full Name
phosphodiesterase 6D, cGMP-specific, rod, delta
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Background
Retinal rod rhodopsin-sensitive cGMP 3,5-cyclic phosphodiesterase subunit delta is an enzyme that in humans is encoded by the PDE6D gene. -
Synonyms
PDE6D; phosphodiesterase 6D, cGMP-specific, rod, delta; retinal rod rhodopsin-sensitive cGMP 3,5-cyclic phosphodiesterase subunit delta; 5-cyclic phosphodiesterase subunit delta; GMP PDE delta; GMP-PDE delta; p17 protein; PDE 6; PDE 6D; PDE D; PDE6; PDE6D_HUMAN; PDED; Phosphodiesterase 6D cGMP specific; Phosphodiesterase 6D cGMP specific rod delta; Protein p17; Retinal rod photoreceptor cGMP phosphodiesterase delta; Retinal rod rhodopsin sensitive cGMP 3 5 cyclic phosphodiesterase subunit delta; Retinal rod rhodopsin-sensitive cGMP 3; OTTHUMP00000204402; OTTHUMP00000204404;
- Involved Pathway
- Protein Function
- Interacting Protein
PDE6D involved in several pathways and played different roles in them. We selected most pathways PDE6D participated on our site, such as Purine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDE6D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Purine metabolism | NME1-NME2;RRM2;GUCY1B3;PRPS1A;PRIM1;PNP6;CANT1;NT5C1AA;HPRT1 |
PDE6D has several biochemical functions, for example, 3,5-cyclic-nucleotide phosphodiesterase activity, GTPase inhibitor activity, Rab GTPase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDE6D itself. We selected most functions PDE6D had, and list some proteins which have the same functions with PDE6D. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 3,5-cyclic-nucleotide phosphodiesterase activity | PDE5AB;PDE10A;PDE3B;PDE5A;PDE9A;PDE4D;PDE6D;PDE11A;PDE8B |
| GTPase inhibitor activity | CPEB2;ARL2;SLIT2;RHOH;UBE4A;RTKN;PDE6D;GPS1;GPS2 |
| Rab GTPase binding | EXPH5;ANKFY1;FER;RABGAP1L;RABGEF1;RUSC2;SYTL4;CFAP45;ANKRD27 |
| protein binding | LOC729991;CACNA1SB;EFEMP1;CETN1;MUC7;ANKRD1;DENND2D;LRRC25;DNA2 |
PDE6D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDE6D here. Most of them are supplied by our site. Hope this information will be useful for your research of PDE6D.
ARL2; Arl2; RPGR
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