Recombinant Full Length Human PDE6D Protein, C-Flag-tagged

Cat.No. : PDE6D-480HFL
Product Overview : Recombinant Full Length Human PDE6D Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.
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Description : This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants.
Source : Mammalian cells
Species : Human
Tag : Flag
Form : 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 17.2 kDa
AA Sequence : MSAKDERAREILRGFKLNWMNLRDA ETGKILWQGTEDLSVPGVEHEARVP KKILKCKAVSRELNFSSTEQ MEKFRLEQKVYFKGQCLEEWFFEFG FVIPNSTNTWQSLIEAAPESQMMPA SVLTGNVIIETKFFDDDLLV
STSRVRLFYVTRTRPLEQKLISEED LAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining.
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade.
Concentration : >50 ug/mL as determined by microplate BCA method.
Preparation : Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Pathways : Progesterone-mediated oocyte maturation, Purine metabolism
SDS-PAGE: Coomassie blue staining of purified PDE6D protein.
Gene Name : PDE6D phosphodiesterase 6D [ Homo sapiens (human) ]
Official Symbol : PDE6D
Synonyms : PDED; JBTS22
Gene ID : 5147
mRNA Refseq : NM_002601.4
Protein Refseq : NP_002592.1
MIM : 602676
UniProt ID : O43924

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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