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Official Full Name PDZ and LIM domain 3
Background The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. This gene is found near a region of chromosome 4 that has been implicated in facioscapulohumeral muscular dystrophy, but this gene does not appear to be involved in the disease. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms PDLIM3; PDZ and LIM domain 3; PDZ and LIM domain protein 3; ALP; Actinin associated LIM protein; Actinin-associated LIM protein; Alpha actinin 2 associated LIM protein; Alpha-actinin-2-associated LIM protein; DKFZp686L0362; Enigma homolog; PDLI3_HUMAN; PDLIM 3
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PDLIM3-1324HCL Recombinant Human PDLIM3 cell lysate N/A
    Human PDLIM3-1622H Recombinant Human PDLIM3, GST-tagged E.coli GST
    Human PDLIM3-822H Recombinant Human PDLIM3 Protein, His-tagged E.coli His
    Mouse PDLIM3-12588M Recombinant Mouse PDLIM3 Protein Mammalian Cell His
    Rat PDLIM3-4353R Recombinant Rat PDLIM3 Protein Mammalian Cell His
    Rhesus Macaque PDLIM3-3360R Recombinant Rhesus monkey PDLIM3 Protein, His-tagged Mammalian Cell His
    Chicken PDLIM3-1159C Recombinant Chicken PDLIM3 Mammalian Cell His

    pdlim3 involved in several pathways and played different roles in them. We selected most pathways pdlim3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with pdlim3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    pdlim3 has several biochemical functions, for example, cytoskeletal protein binding, protein binding, structural constituent of muscle. Some of the functions are cooperated with other proteins, some of the functions could acted by pdlim3 itself. We selected most functions pdlim3 had, and list some proteins which have the same functions with pdlim3. You can find most of the proteins on our site.

    Function Related Protein
    cytoskeletal protein binding ALDOB; DES; TPM1; EPB4.1L4A; ANXA2A; EPB41L5; EPB41L3B; ANXA2; MSNA; PDLIM3
    protein binding ZNF410; ACSS1; DACT2; RAB11FIP2; EPB41B; GLI3; PTPN18; PTK6; RMND1; CCNT1
    structural constituent of muscle TPM1; MYL1; NEXN; PDLIM3; ACTN2; TPM4; MYOM1; MYL6; MYL9; MYBPH
    zinc ion binding BTR29; NR2F1A; PITRM1; MUL1B; PRKCBA; SOD1; ZMYND11; ADAM10B; ESRRB; TRAF7

    pdlim3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with pdlim3 here. Most of them are supplied by our site. Hope this information will be useful for your research of pdlim3.


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