PDP2

  • Official Full Name

    pyruvate dehyrogenase phosphatase catalytic subunit 2

  • Overview

    Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.
  • Synonyms

    PDP2; pyruvate dehyrogenase phosphatase catalytic subunit 2; [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial; KIAA1348; PPM2C2; protein phosphatase 2C; magnesium dependent; catalytic subunit 2; mitochondrial; [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2; MSP46; PDP 2; PDP2_HUMAN; PDPC 2; Pyruvate dehydrogenase phosphatase 2; Pyruvate dehydrogenase phosphatase catalytic subunit 2; pyruvate dehydrogenase phosphatase isoenzyme 2; Pyruvate dehydrogenase phosphatase, catalytic subunit 2; protein phosphatase 2C, magnesium-dependent, catalytic subunit 2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PDP2-30496TH Recombinant Human PDP2, His-tagged His 463 amino acids
Human PDP2-1715H Recombinant Human PDP2 Mammalian Cell His
Human PDP2-8201H Recombinant Human PDP2 protein, His & T7-tagged E.coli His/T7 Met1~Ile186 (Accession # Q9P2J9)
Human PDP2-699H Recombinant Human PDP2, His-tagged E.coli His
Human PDP2-3323HCL Recombinant Human PDP2 293 Cell Lysate HEK293 N/A
Human PDP2-3824H Recombinant Human PDP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human PDP2-1128H Recombinant Human PDP2 Protein (67-529 aa), His-tagged E.coli His 67-529 aa
Human PDP2-3824H-B Recombinant Human PDP2 Protein Pre-coupled Magnetic Beads HEK293
Mouse Pdp2-4776M Recombinant Mouse Pdp2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat PDP2-4356R Recombinant Rat PDP2 Protein Mammalian Cell His
Rat Pdp2-8202R Recombinant Rat Pdp2 protein, His & T7-tagged E.coli His/T7 Met1~Ile187 (Accession # O88484)
Rat PDP2-4016R-B Recombinant Rat PDP2 Protein Pre-coupled Magnetic Beads HEK293
Rat PDP2-4016R Recombinant Rat PDP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque PDP2-3362R Recombinant Rhesus monkey PDP2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque PDP2-3180R-B Recombinant Rhesus Macaque PDP2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque PDP2-3180R Recombinant Rhesus Macaque PDP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish PDP2-9163Z Recombinant Zebrafish PDP2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

PDP2 involved in several pathways and played different roles in them. We selected most pathways PDP2 participated on our site, such as Metabolism, Pyruvate metabolism, Pyruvate metabolism and Citric Acid (TCA) cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MetabolismPIK3R6;CYP3C4;BCKDK;ACSF2;AZIN2;B3GNT3;SLC16A8;MED19;SURF1
Pyruvate metabolismMDH1;ACACB;LDHBB;PDHA1B;GRHPRB;LDHD;PKMA;GRHPR;ALDH2
Pyruvate metabolism and Citric Acid (TCA) cycleADHFE1;PDK2B;PDP1;PDK3;SLC16A8;BRP44;SLC16A1;PDK2;MPC1
Regulation of pyruvate dehydrogenase (PDH) complexPDP2;PDK2B;PDK3B;PDPR;PDK3;PDK4;PDK2;PDP1
The citric acid (TCA) cycle and respiratory electron transportNDUFAF6;ETFA;COX16;TACO1;PDP2;C20orf7;PDK3;NDUFAF3;SLC25A27

PDP2 has several biochemical functions, for example, [pyruvate dehydrogenase (lipoamide)] phosphatase activity, metal ion binding, protein serine/threonine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PDP2 itself. We selected most functions PDP2 had, and list some proteins which have the same functions with PDP2. You can find most of the proteins on our site.

Function Related Protein
[pyruvate dehydrogenase (lipoamide)] phosphatase activityPDP1;PDP2
metal ion bindingARSI;LIG1;ZFP319;SP8B;CYP2P10;LYAR;TAE1;TERT;ZNF498
protein serine/threonine phosphatase activityPPP3CA;PPM1AA;CDC14A;PPM1G;PHLPP2;CDC14B;PPP5C;CTDNEP1A;PPEF1

PDP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PDP2.

Research Area

Related articles

Belykh, LB; Skripov, NI; et al. The Catalytic Properties of Pd Nanoparticles Modified by Phosphorus in Liquid-phase Hydrogenation of o-chloronitrobenzene. CURRENT NANOSCIENCE 11:175-185(2015).
Rellinger, EJ; Romain, C; et al. Silencing Gastrin-Releasing Peptide Receptor Suppresses Key Regulators of Aerobic Glycolysis in Neuroblastoma Cells. PEDIATRIC BLOOD & CANCER 62:581-586(2014).
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