PDP2 Protein

PDP2

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PDP2

Official Full Name pyruvate dehyrogenase phosphatase catalytic subunit 2
Background Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.
Synonyms PDP2; pyruvate dehyrogenase phosphatase catalytic subunit 2; [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial; KIAA1348; PPM2C2; protein phosphatase 2C; magnesium dependent; catalytic subunit 2; mitochondrial; [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2; MSP46; PDP 2; PDP2_HUMAN; PDPC 2; Pyruvate dehydrogenase phosphatase 2; Pyruvate dehydrogenase phosphatase catalytic subunit 2; pyruvate dehydrogenase phosphatase isoenzyme 2; Pyruvate dehydrogenase phosphatase, catalytic subunit 2; protein phosphatase 2C, magnesium-dependent, catalytic subunit 2;
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • His (Fc)-Avi
    • T7
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PDP2-1715H Recombinant Human PDP2 Mammalian Cell His Inquiry
    Human PDP2-30496TH Recombinant Human PDP2, His-tagged His Inquiry
    Human PDP2-699H Recombinant Human PDP2, His-tagged E.coli His Inquiry
    Human PDP2-8201H Recombinant Human PDP2 protein, His & T7-tagged E.coli His/T7 Inquiry
    Rat PDP2-4356R Recombinant Rat PDP2 Protein Mammalian Cell His Inquiry
    Rat Pdp2-8202R Recombinant Rat Pdp2 protein, His & T7-tagged E.coli His/T7 Inquiry
    Rhesus Macaque PDP2-3362R Recombinant Rhesus monkey PDP2 Protein, His-tagged Mammalian Cell His Inquiry
    Zebrafish PDP2-9163Z Recombinant Zebrafish PDP2 Mammalian Cell His Inquiry
    Human PDP2-3323HCL Recombinant Human PDP2 293 Cell Lysate HEK293 N/A Inquiry
    Rhesus Macaque PDP2-3180R Recombinant Rhesus Macaque PDP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi Inquiry
    Human PDP2-3824H Recombinant Human PDP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi Inquiry
    Rat PDP2-4016R Recombinant Rat PDP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi Inquiry
    Human PDP2-1128H Recombinant Human PDP2 Protein (67-529 aa), His-tagged E.coli His Inquiry
    Mouse Pdp2-4776M Recombinant Mouse Pdp2 Protein, Myc/DDK-tagged HEK293T Myc/DDK Inquiry

    PDP2 involved in several pathways and played different roles in them. We selected most pathways PDP2 participated on our site, such as Metabolism, Pyruvate metabolism, Pyruvate metabolism and Citric Acid (TCA) cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism AWAT1; B3GNT3; OXSR1; SLC25A2; SAT1B; MED31; OSBP; ARSJ; BSG; MOCOS
    Pyruvate metabolism ALDH9A1A.1; LDHAL6A; PDK2B; hchA; DLAT; PDHB; ALDH1B1; PDP2; PDHA1B; ALDH3A2
    Pyruvate metabolism and Citric Acid (TCA) cycle SLC16A1; PDK2B; PDP2; PDK3; PDP1; SLC16A8; PDK2; PDK4; PDK3B; ADHFE1
    Regulation of pyruvate dehydrogenase (PDH) complex PDP2; PDK2B; PDK4; PDK2; PDP1; PDPR; PDK3B; PDK3
    The citric acid (TCA) cycle and respiratory electron transport COX16; ATP5S; UCP3; SCO1; PDP2; NDUFAF6; C2orf56; UCP2; BRP44; SURF1

    PDP2 has several biochemical functions, for example, [pyruvate dehydrogenase (lipoamide)] phosphatase activity, metal ion binding, protein serine/threonine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PDP2 itself. We selected most functions PDP2 had, and list some proteins which have the same functions with PDP2. You can find most of the proteins on our site.

    Function Related Protein
    [pyruvate dehydrogenase (lipoamide)] phosphatase activity PDP2; PDP1
    metal ion binding TH2; ZSWIM4; ZNF689; MAN1A; MBLAC2; PLEKHM1P; ZNF23; TRIM50; VSNL1A; ATF7
    protein serine/threonine phosphatase activity DUSP23B; PTEN; CDC14AB; PPM1BB; PPM1J; PPM1AB; PPM1H; PPP1R15B; ILKAP; PPM1B

    PDP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PDP2.

    Belykh, LB; Skripov, NI; et al. The Catalytic Properties of Pd Nanoparticles Modified by Phosphorus in Liquid-phase Hydrogenation of o-chloronitrobenzene. CURRENT NANOSCIENCE 11:175-185(2015).
    Rellinger, EJ; Romain, C; et al. Silencing Gastrin-Releasing Peptide Receptor Suppresses Key Regulators of Aerobic Glycolysis in Neuroblastoma Cells. PEDIATRIC BLOOD & CANCER 62:581-586(2014).

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