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PEMT

  • Official Full Name

    phosphatidylethanolamine N-methyltransferase

  • Synonyms

    PEMT;phosphatidylethanolamine N-methyltransferase;8830;ENSG00000133027;PNMT;PEAMT;PEMPT;PEMT2;17p11.2;MGC2483;phosphatidylethanolamine N-methyltransferase;phosphatidylethanolamine N-methyltransferase;EC 2.1.1.17;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PEMT-3299HCL Recombinant Human PEMT 293 Cell Lysate HEK293 N/A
Human PEMT-3300HCL Recombinant Human PEMT 293 Cell Lysate HEK293 N/A
Human PEMT-3301HCL Recombinant Human PEMT 293 Cell Lysate HEK293 N/A
Human PEMT-1798H Recombinant Human PEMT protein, GST-tagged E.coli GST 1-236 aa
Mouse Pemt-4792M Recombinant Mouse Pemt Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat PEMT-4374R Recombinant Rat PEMT Protein Mammalian Cell His
Rat PEMT-4034R Recombinant Rat PEMT Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PEMT-4034R-B Recombinant Rat PEMT Protein Pre-coupled Magnetic Beads HEK293
Bos taurus (Bovine) RFL36327BF Recombinant Full Length Bovine Phosphatidylethanolamine N-Methyltransferase(Pemt) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-199)
Homo sapiens (Human) RFL21580HF Recombinant Full Length Human Phosphatidylethanolamine N-Methyltransferase(Pemt) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-199)
Mus musculus (Mouse) RFL11667MF Recombinant Full Length Mouse Phosphatidylethanolamine N-Methyltransferase(Pemt) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-199)
Rattus norvegicus (Rat) RFL35389RF Recombinant Full Length Rat Phosphatidylethanolamine N-Methyltransferase(Pemt) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-199)
Zebrafish PEMT-10505Z Recombinant Zebrafish PEMT Mammalian Cell His
Chicken PEMT-1315C Recombinant Chicken PEMT Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PEMT Related Articles
  • PEMT Related Research Area

PEMT involved in several pathways and played different roles in them. We selected most pathways PEMT participated on our site, such as Acetylcholine Synthesis, Glycerophospholipid biosynthesis, Glycerophospholipid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PEMT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Acetylcholine SynthesisCHAT;CHKA;PEMT
Glycerophospholipid biosynthesisCPNE7;AGPAT1;CEPT1A;STIL;CHKA;CDIPT;CPNE1;PITPNB;PLA2G16
Glycerophospholipid metabolismPLA2G4F;GPCPD1;PLA2G4C;PPAP2A;LPCAT4;ETNK2;AGPAT9;CDS1;PLA2G4A
Metabolic pathwaysPDXP;FASN;SMPD1;FAM213B;UQCR11;HSD17B12B;MAT2AB;HMGCS1;MIBP
MetabolismSLC25A15B;PDK2B;SLC16A1;AMDHD1;MED9;MTF1;SLC35B2;SACM1LB;B3GNT2A
Metabolism of lipids and lipoproteinsLBR;APOA4B.2;ARSF;VAPB;ACOT6;MED15;ARV1;SPTLC1;MED8
Phospholipid metabolismDGAT1B;SACM1LB;CHKB;CDS1;ABHD4;TPTE;ABHD3;CPNE7;PLD6
Synthesis of PCPHOSPHO1;SLC44A5B;CEPT1A;ABHD3;CEPT1;PEMT

PEMT has several biochemical functions, for example, phosphatidyl-N-dimethylethanolamine N-methyltransferase activity, phosphatidyl-N-methylethanolamine N-methyltransferase activity, phosphatidylethanolamine N-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PEMT itself. We selected most functions PEMT had, and list some proteins which have the same functions with PEMT. You can find most of the proteins on our site.

Function Related Protein
phosphatidyl-N-dimethylethanolamine N-methyltransferase activity
phosphatidyl-N-methylethanolamine N-methyltransferase activity
phosphatidylethanolamine N-methyltransferase activity
phosphatidylethanolamine bindingNF1;ESYT2;LC3;PEBP1;PEMT;MFGE8;ANXA11;CD300A

PEMT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PEMT here. Most of them are supplied by our site. Hope this information will be useful for your research of PEMT.

Gao, X; van der Veen, JN; et al. Vagus nerve contributes to the development of steatohepatitis and obesity in phosphatidylethanolamine N-methyltransferase deficient mice. JOURNAL OF HEPATOLOGY 62:913-920(2015).
Kohjima, M; Enjoji, M; et al. Pathophysiological analysis of primary biliary cirrhosis focusing on choline/phospholipid metabolism. LIVER INTERNATIONAL 35:1095-1102(2015).
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