PFKFB2
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Official Full Name
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 -
Synonyms
PFKFB2;6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2;8873;ENSG00000123836;PFK-2/FBPase-2;1q31;MGC138308, MGC138310, DKFZp781D2217;6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2;6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2;PFK/FBPase 2;PFKFB, cardiac;6PF-2-K/Fru-2,6-P2ase 2;6PF-2-K/Fru-2,6-P2ASE heart-type isozyme;fructose-2,6-bisphosphatase, cardiac isozyme;EC 2.7.1.105 EC 3.1.3.46
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Mouse
- E.coli
- Mammalian Cells
- Sf9 Cells
- HEK293
- Yeast
- Baculovirus
- Mammalian cells
- His
- GST
- Non
- Avi
- Fc
Involved Pathway
PFKFB2 involved in several pathways and played different roles in them. We selected most pathways PFKFB2 participated on our site, such as Fructose and mannose metabolism,AMPK signaling pathway,Thyroid hormone signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PFKFB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fructose and mannose metabolism | FUK,AKR1B1,HK1,PFKFB4L,TSTA3,HK2,GMPPAA,TPI1A,ALDOC,PFKFB4 |
| AMPK signaling pathway | EIF4EBP1,PIK3CB,AKT1S1,STK11,ADRa1A,PPP2R2A,PCK1,CREB3,RAB10,CREB3L1 |
| Thyroid hormone signaling pathway | PRKCA,DIO3,SIN3A,TP53,SRC,SLC2A1,MED27,MED12L,PDPK1,SLC16A10 |
Protein Function
PFKFB2 has several biochemical functions, for example, 6-phosphofructo-2-kinase activity,ATP binding,fructose-2,6-bisphosphate 2-phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PFKFB2 itself. We selected most functions PFKFB2 had, and list some proteins which have the same functions with PFKFB2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| fructose-2,6-bisphosphate 2-phosphatase activity | C12orf5,PFKFB3,PFKFB4,TIGARB,TIGARA,PFKFB1 |
| protein kinase binding | PIFO,FAM83A,BCL2L14,CDK5RAP2,DLG1,KAT2B,TP53,CALM3,FGR,GCSAM |
| ATP binding | PRKDC,MYH4,MYO3B,UBE2L3A,ADK,DCLK1A,LANCL2,DHX15,STK25B,ADCK3 |
| 6-phosphofructo-2-kinase activity | PFKFB1,PFKFB4L,PFKFB3,PFKFB4,PFKFB2A |
| protein binding | PLXDC1,VPS4B,COPS4,IL18R1,TERT,PPP4R4,OIP5,CORO1A,KLHL12,UCHL1 |
Interacting Protein
PFKFB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PFKFB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PFKFB2.
YWHAG;YWHAZ;ribD;1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate;h0yhg0_human;SRRM2;ZC3H11A;TRIM21;YWHAB;SARNP;YWHAH;PDE4D;FAM83B;CPSF7;DOCK8;RBM15;RMDN3;POLDIP3;ZCCHC17;PGAP2
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