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PFKFB2

Official Full Name

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
Synonyms

PFKFB2;6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2;8873;ENSG00000123836;PFK-2/FBPase-2;1q31;MGC138308, MGC138310, DKFZp781D2217;6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2;6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2;PFK/FBPase 2;PFKFB, cardiac;6PF-2-K/Fru-2,6-P2ase 2;6PF-2-K/Fru-2,6-P2ASE heart-type isozyme;fructose-2,6-bisphosphatase, cardiac isozyme;EC 2.7.1.105 EC 3.1.3.46;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Rat
Rhesus Macaque

Source

E.coli
HEK293
Mammalian Cell
Sf9 Insect Cell

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PFKFB2-67H	Recombinant Human PFKFB2, GST-tagged	Sf9 Insect Cell	GST		Inquiry
Human	PFKFB2-643H	Recombinant Human PFKFB2 Protein, His-tagged	E.coli	His		Inquiry
Human	PFKFB2-3275HCL	Recombinant Human PFKFB2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	PFKFB2-4009H	Recombinant Human PFKFB2 protein, His-tagged	E.coli	His	1-350 aa	$319 / 25ug
Rat	PFKFB2-4391R	Recombinant Rat PFKFB2 Protein	Mammalian Cell	His		Inquiry
Rat	PFKFB2-4051R	Recombinant Rat PFKFB2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	PFKFB2-4051R-B	Recombinant Rat PFKFB2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	PFKFB2-3384R	Recombinant Rhesus monkey PFKFB2 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	PFKFB2-3202R	Recombinant Rhesus Macaque PFKFB2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	PFKFB2-3202R-B	Recombinant Rhesus Macaque PFKFB2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein

PFKFB2 involved in several pathways and played different roles in them. We selected most pathways PFKFB2 participated on our site, such as Fructose and mannose metabolism, AMPK signaling pathway, Thyroid hormone signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PFKFB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Fructose and mannose metabolism	AKR1B10;GMPPAB;GMPPAA;ALDOAB;HK2;HKDC1;PFKFB2A;PFKFB3;PFKFB1
AMPK signaling pathway	PPP2CA;INS2;RAB11B;EEF2;INSR;FASN;CAMKK2;PIK3R5;PPP2R2C
Thyroid hormone signaling pathway	PLCD1;PIK3R1;MDM2;NOTCH1;MED12L;PLCB3;NOTCH3;PIK3R2;ATP1A1

PFKFB2 has several biochemical functions, for example, 6-phosphofructo-2-kinase activity, ATP binding, fructose-2,6-bisphosphate 2-phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PFKFB2 itself. We selected most functions PFKFB2 had, and list some proteins which have the same functions with PFKFB2. You can find most of the proteins on our site.

Function	Related Protein
6-phosphofructo-2-kinase activity	PFKFB2;PFKFB1;PFKFB3;PFKFB2A;PFKFB4;PFKFB4L
ATP binding	TOR2A;NME3;TTBK2;MTHFD1L;DGKB;OASL2;PRKCBA;PRKACAB;MSH4
fructose-2,6-bisphosphate 2-phosphatase activity	PFKFB2;C12orf5;PFKFB3;TIGARB;TIGARA;PFKFB4;PFKFB1
protein binding	ADCK5;IER3;CSTF1;CRNKL1;TIMELESS;HPS1;CLEC16A;METAP2;TNNI3
protein kinase binding	RHEB;PTPN6;CCNE1;MAP2K3;HCLS1;PRKACA;AURKA;LAX1;IKBKB

PFKFB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PFKFB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PFKFB2.

YWHAG; YWHAZ; ribD; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate; h0yhg0_human; SRRM2; ZC3H11A; TRIM21; YWHAB; SARNP; YWHAH; PDE4D; FAM83B; CPSF7; DOCK8; RBM15; RMDN3; POLDIP3; ZCCHC17; PGAP2