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Recombinant Human PFKFB2 Protein, His-tagged

Cat.No. : PFKFB2-643H
Product Overview : Recombinant Human PFKFB2, transcript variant 1, fused with His tag at N-terminal was expressed in E. coli.
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Description : The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.
Source : E. coli
Species : Human
Tag : His
Form : 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.
Molecular Mass : 58.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 [ Homo sapiens ]
Official Symbol : PFKFB2
Synonyms : PFK-2/FBPase-2
Gene ID : 5208
mRNA Refseq : NM_006212.2
Protein Refseq : NP_006203.2
MIM : 171835
UniProt ID : O60825

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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