pgam2 Protein, phosphoglycerate mutase 2 (muscle)

pgam2

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pgam2

Official Full Name phosphoglycerate mutase 2 (muscle)
Background Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). This gene encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X.
Synonyms PGAM2; phosphoglycerate mutase 2 (muscle); phosphoglycerate mutase 2; PGAM M; BPG dependent PGAM 2; BPG-dependent PGAM 2; GSD10; MGC88743; Muscle specific phosphoglycerate mutase; Muscle-specific phosphoglycerate mutase; OTTHUMP00000207787; PGAM-M; PGAM2_HUMAN; PGAMM; Phosphoglycerate mutase isozyme M
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PGAM2-1163H Recombinant Human PGAM2 Mammalian Cell His
    Human PGAM2-15H Recombinant Human PGAM2 protein, His-tagged (Bioactivity Validated) E.coli His
    Human PGAM2-1662H Recombinant Human PGAM2, GST-tagged E.coli GST
    Human PGAM2-1932H Recombinant Human Phosphoglycerate Mutase 2 (muscle), His-tagged His
    Human PGAM2-3263HCL Recombinant Human PGAM2 293 Cell Lysate HEK293 N/A
    Mouse PGAM2-12674M Recombinant Mouse PGAM2 Protein Mammalian Cell His
    Mouse Pgam2-1744M Recombinant Mouse Pgam2 protein, His & T7-tagged E.coli His/T7
    Rat PGAM2-4400R Recombinant Rat PGAM2 Protein Mammalian Cell His
    Zebrafish PGAM2-11256Z Recombinant Zebrafish PGAM2 Mammalian Cell His

    pgam2 involved in several pathways and played different roles in them. We selected most pathways pgam2 participated on our site, such as Glycolysis / Gluconeogenesis, Glycine, serine and threonine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with pgam2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycolysis / Gluconeogenesis ALDH9A1A.1; LDHB; PGK2; ADH2-1; PGM1; HK2; G6PC2; GM5506; GPIA; PCK2
    Glycine, serine and threonine metabolism AOC2; AGXTA; SHMT1; PHGDH; MAOB; MAOA; SARDH; ALAS2; DAO; PGAM1A
    Metabolic pathways ADH4; MTMR7A; CYP2C50; AANAT1; ATP6V0A1; RDH10; CYP2C8; LALBA; ALOX12; HYAL2
    Carbon metabolism TKTL2; GPIA; GLUD2; DLAT; MDH1AA; IDH3B; ESD; AGXT; GLUD1; RGN
    Biosynthesis of amino acids PGAM2; SDSL; GOT2; pykF; MAT2B; GLUL; BCAT2; GOT2B; CTH; ACO1
    Glucagon signaling pathway CREB5; GNAQ; SIK2; PYGM; SMEK2; PPP3CB; PRKAB1; ITPR1; CALM4; PYGL
    Central carbon metabolism in cancer RAF1; PKM2; PIK3CD; PIK3R5; HK1; SCO2; AKT2; PIK3R2; TP53; FGFR1

    pgam2 has several biochemical functions, for example, 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity, bisphosphoglycerate 2-phosphatase activity, bisphosphoglycerate mutase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by pgam2 itself. We selected most functions pgam2 had, and list some proteins which have the same functions with pgam2. You can find most of the proteins on our site.

    Function Related Protein
    2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity PGAM2; PGAM1B; PGAM1A
    bisphosphoglycerate 2-phosphatase activity BPGM; C12orf5; PGAM1; TIGARA; PGAM2; TIGARB
    bisphosphoglycerate mutase activity PGAM2; BPGM; PGAM1
    cofactor binding C3; DDO; HACL1; DAO; ASNS; ACLYA; UROS; LMO2; PHYH; TYMS
    phosphoglycerate mutase activity PGAM1B; PGAM2; PGAM1A; PGAM1; BPGM

    pgam2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with pgam2 here. Most of them are supplied by our site. Hope this information will be useful for your research of pgam2.

    USP15; NS; GABARAPL1; SH3GLB1

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