Recombinant Full Length Human PGAM2 Protein, C-Flag-tagged

• Cat.No.: PGAM2-1997HFL
• Product Overview: Recombinant Full Length Human PGAM2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). This gene encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 28.6 kDa
• AA Sequence: MATHRLVMVRHGESTWNQENRFCGW FDAELSEKGTEEAKRGAKAIKDAKM EFDICYTSVLKRAIRTLWAI LDGTDQMWLPVVRTWRLNERHYGGL TGLNKAETAAKHGEEQVKIWRRSFD IPPPPMDEKHPYYNSISKER RYAGLKPGELPTCESLKDTIARALP FWNEEIVPQIKAGKRVLIAAHGNSL RGIVKHLEGMSDQAIMELNL PTGIPIVYELNKELKPTKPMQFLGD EETVRKAMEAVAAQGKAK TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome
• Protein Pathways: Glycolysis / Gluconeogenesis, Metabolic pathways

Gene Information

• Gene Name: PGAM2 phosphoglycerate mutase 2 [ Homo sapiens (human) ]
• Official Symbol: PGAM2
• Synonyms: GSD10, PGAM-M, PGAMM
• Gene ID: 5224
• mRNA Refseq: NM_000290.4
• Protein Refseq: NP_000281.2
• MIM: 612931
• UniProt ID: P15259