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Official Full Name phosphatidylinositol glycan anchor biosynthesis, class C
Background This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI) lipid anchor biosynthesis. The GPI lipid anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. The encoded protein is one subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. Two alternatively spliced transcripts that encode the same protein have been found for this gene. A pseudogene on chromosome 11 has also been characterized.
Synonyms PIGC; phosphatidylinositol glycan anchor biosynthesis, class C; phosphatidylinositol glycan, class C; phosphatidylinositol N-acetylglucosaminyltransferase subunit C; GPI2; Phosphatidylinositol glycan biosynthesis class C protein; Phosphatidylinositol N acetylglucosaminyltransferase subunit C; PIG-C; OTTHUMP00000032652; phosphatidylinositol-glycan biosynthesis class C protein; phosphatidylinositol-glycan biosynthesis, class C protein
    • Species :
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • Mammalian Cell
    • Tag :
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse PIGC-12779M Recombinant Mouse PIGC Protein Mammalian Cell His
    Rat PIGC-4448R Recombinant Rat PIGC Protein Mammalian Cell His
    Rhesus Macaque PIGC-3426R Recombinant Rhesus monkey PIGC Protein, His-tagged Mammalian Cell His
    Zebrafish PIGC-12458Z Recombinant Zebrafish PIGC Mammalian Cell His

    PIGC involved in several pathways and played different roles in them. We selected most pathways PIGC participated on our site, such as Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PIGC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycosylphosphatidylinositol(GPI)-anchor biosynthesis PIGO; GPLD1; PIGP; PIGM; PIGYL; PIGH; PIGS; PIGU; PIGX; PIGB
    Metabolic pathways CYP3A5; GCLM; NT5C3B; ACSL4B; ADSS; RRM1; MTMR3; NDUFB6; PTGDSB; PKMB

    PIGC has several biochemical functions, for example, 7S RNA binding, GDP binding, GTP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PIGC itself. We selected most functions PIGC had, and list some proteins which have the same functions with PIGC. You can find most of the proteins on our site.

    Function Related Protein
    7S RNA binding SRP19; SRP14; EXOSC2; SRP54; PIGC; SRP68; SRP9; SRP72; SRP54A
    GDP binding SRP54B; RAB5B; SEPT12; ARL8B; ARL2; KRAS; RAB5C; RAB7A; RAB18; RAP1B
    GTP binding RAB39BB; Arf2; MB21D1; SEPT9B; RNF112; RRAD; GIMAP2; IFT27; GBP1; SCG5
    contributes_to GTPase activity SRP54; PIGC; SRP54B; SRP54A
    drug binding MTOR; PDE10A; CHRM1; CHRNB4; DRD3; PDE4D; SLC6A4A; SMO; PDXK; GRIK1
    endoplasmic reticulum signal peptide binding PIGC; SRP68; SRP14; SRP54; SRP54B; SRP54A
    poly(A) RNA binding ZCCHC11; FAM120B; DAP3; YTHDF2; DDX46; RARS2; RPL3; RPS13; NOP16; PIGC
    ribonucleoprotein complex binding PIGC; PPIH; PRMT5; IFIH1; PES1; PRPF31; SRP54A; TIMM50; SRP54; CD2BP2

    PIGC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PIGC here. Most of them are supplied by our site. Hope this information will be useful for your research of PIGC.

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