pigk Protein, phosphatidylinositol glycan anchor biosynthesis, class K


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Official Full Name phosphatidylinositol glycan anchor biosynthesis, class K
Background This gene encodes a member of the cysteine protease family C13 that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is a member of the multisubunit enzyme, GPI transamidase and is thought to be its enzymatic component. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins.
Synonyms PIGK; phosphatidylinositol glycan anchor biosynthesis, class K; phosphatidylinositol glycan, class K; GPI-anchor transamidase; GPI transamidase subunit; GPI8; hGPI8; PIG-K; GPI8 homolog; phosphatidylinositol-glycan biosynthesis class K protein; MGC22559
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PIGK-1706H Recombinant Human PIGK, His-tagged E.coli His
    Human PIGK-3197HCL Recombinant Human PIGK 293 Cell Lysate HEK293 N/A
    Mouse PIGK-12781M Recombinant Mouse PIGK Protein Mammalian Cell His
    Rhesus Macaque PIGK-3427R Recombinant Rhesus monkey PIGK Protein, His-tagged Mammalian Cell His
    Chicken PIGK-2935C Recombinant Chicken PIGK Mammalian Cell His
    Zebrafish PIGK-373Z Recombinant Zebrafish PIGK Mammalian Cell His

    pigk involved in several pathways and played different roles in them. We selected most pathways pigk participated on our site, such as Attachment of GPI anchor to uPAR, Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with pigk were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Attachment of GPI anchor to uPAR PIGK
    Glycosylphosphatidylinositol(GPI)-anchor biosynthesis PIGV; PIGQ; PIGO; PIGK; DPM2; PIGX; PIGF; PIGA; PIGB; PIGN
    Metabolic pathways CYP2C8; SAT2; LDHC; CES1C; GALNT5; PFAS; B3GALT2; GATM; ACSL1; Ckmm
    Metabolism of proteins B3GNT8; NAPB; TOMM20; PFDN4; YIF1A; TRAPPC6B; ST3GAL3A; MAN1B1; DMBT1; CCT6A
    Post-translational modification: synthesis of GPI-anchored proteins PIGK
    Post-translational protein modification C8orf84; EID3; SEC22C; MPDU1A; ADAMTSL5; GALNTL5; DNAJC24; PHC2; MUC12; GALNT5

    pigk has several biochemical functions, for example, contributes_to GPI anchor binding, GPI-anchor transamidase activity, cysteine-type peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by pigk itself. We selected most functions pigk had, and list some proteins which have the same functions with pigk. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to GPI anchor binding GPAA1; PIGK
    GPI-anchor transamidase activity FAM108C; PIGK; FAM108A; MBLAC1; FAM108B; PIGU; NUDT13
    cysteine-type peptidase activity CASP8L1; SENP7; Casp3; USP17L3; SENP8; CASPC; CASP8; USP9; USP17L1P; CASP6
    protein binding SMYD1; MTAP1B; BCL2L2; GSDMA2; ROCK2; TMEM231; CASC3; F10; FAM207A; GATA2
    protein disulfide isomerase activity PDIA4; PDIP5; PDIA3; QSOX1; ERO1LB; P4HB; TMX1; PDIA2; TXNDC5; PDIA6

    pigk has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with pigk here. Most of them are supplied by our site. Hope this information will be useful for your research of pigk.

    ALPP; midostaurin; PIGS

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