PIGR
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Official Full Name
polymeric immunoglobulin receptor
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Overview
This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene. -
Synonyms
PIGR; polymeric immunoglobulin receptor; poly-Ig receptor; hepatocellular carcinoma associated protein TB6; hepatocellular carcinoma-associated protein TB6; FLJ22667; MGC125361; MGC125362;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Bovine
- Cattle
- Chicken
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Oryctolagus cuniculus (Rabbit)
- Rat
- Rattus norvegicus (Rat)
- Zebrafish
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- Human Cell
- Insect cells
- Mammalian Cell
- Mammalian cells
- Yeast
- C
- 8His
- Fc
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- N
- Twin
- Strep
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | PIGR-495H | Active Recombinant Human PIGR, His-tagged | Mammalian cells | His |
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| Human | PIGR-1470H | Recombinant Human PIGR protein, His-tagged | E.coli | His | Pro462~Ala561 (Accession # P01833) |
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| Human | PIGR-338H | Recombinant Human PIGR | Mammalian Cell | His |
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| Human | PIGR-830H | Recombinant Human PIGR protein, His-tagged | HEK293 | His | 620 |
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| Human | PIGR-829H | Recombinant Human PIGR Protein(Met 1-Arg 638, 365 Ser/Gly), His-tagged | HEK293 | C-His | Met 1-Arg 638, 365 Ser/Gly | |
| Human | PIGR-2868HCL | Recombinant Human PIGR cell lysate | Human Cell | N/A |
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| Human | PIGR-013H | Active Recombinant Human PIGR Protein, His-tagged | Insect cells | His |
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| Human | PIGR-1934H | Recombinant Human PIGR Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK |
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| Human | PIGR-3856H-B | Recombinant Human PIGR Protein Pre-coupled Magnetic Beads | HEK293 |
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| Human | PIGR-36H | Recombinant Human PIGR Protein, C-8His tagged, Biotinylated | HEK293 | C-8His | K19-R638 |
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| Human | pIgR-831H | Recombinant Human pIgR Protein | HEK293 | 764 |
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| Human | PIGR-3856H | Recombinant Human PIGR Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Human | PIGR-4891H | Recombinant Human PIGR Protein (Lys19-Arg638), C-Fc tagged | Mammalian cells | C-Fc | Lys19-Arg638 |
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| Human | PIGR-209H | Recombinant Human PIGR Protein, His-tagged | Human Cell | His |
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| Human | PIGR-4892H | Recombinant Human PIGR Protein (Lys19-Arg638), C-His tagged | Mammalian cells | C-His | Lys19-Arg638 |
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| Human | PIGR-0731H | Recombinant Human PIGR protein, Twin-Strep-tagged | HEK293 | Twin-Strep | Lys19-Arg603 |
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| Human | PIGR-4894H | Recombinant Human PIGR Protein (Arg289-Arg638), N-His tagged | E.coli | N-His | Arg289-Arg638 |
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| Mouse | Pigr-1018M | Active Recombinant Mouse Pigr Protein, His-tagged | Mammalian cells | His | Lys19-Lys645 |
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| Mouse | Pigr-1471M | Recombinant Mouse Pigr protein, His-tagged | E.coli | His | Pro352~Ala457 (Accession # O70570) |
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| Mouse | Pigr-830M | Active Recombinant Mouse Pigr protein, His-tagged | HEK293 | His | Met1-Lys645 | |
| Mouse | Pigr-1472M | Recombinant Mouse Pigr protein, His-tagged | E.coli | His | Pro463~Ala563 (Accession # O70570) |
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| Mouse | PIGR-2867MCL | Recombinant Mouse PIGR cell lysate | Human Cell | N/A |
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| Mouse | Pigr-4856M | Recombinant Mouse Pigr Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
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| Mouse | Pigr-6727M-B | Recombinant Mouse Pigr Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | Pigr-6727M | Recombinant Mouse Pigr Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rat | Pigr-1474R | Recombinant Rat Pigr protein, His-tagged | E.coli | His | Leu343~Arg447 (Accession # P15083) |
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| Rat | Pigr-1475R | Recombinant Rat Pigr protein, His-tagged | E.coli | His | Lys230~Leu331 (Accession # P15083) |
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| Rat | Pigr-1473R | Recombinant Rat Pigr protein, His-tagged | E.coli | His | Leu135~Ser237 (Accession # P15083) |
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| Bovine | PIGR-1483B | Recombinant Bovine PIGR Protein (400-599 aa), His-tagged | Yeast | His | 400-599 aa |
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| Bovine | PIGR-719B | Recombinant Bovine PIGR Protein (400-599 aa), His-tagged | E.coli | His | 400-599 aa |
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| Cattle | PIGR-1468C | Recombinant Cattle PIGR protein, His-tagged | E.coli | His | Ala353~Val457 (Accession # P81265) |
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| Cattle | PIGR-1469C | Recombinant Cattle PIGR protein, His-tagged | E.coli | His | Pro461~Ala560 |
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| Homo sapiens (Human) | RFL4921HF | Recombinant Full Length Human Polymeric Immunoglobulin Receptor(Pigr) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (19-764) |
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| Mus musculus (Mouse) | RFL7342MF | Recombinant Full Length Mouse Polymeric Immunoglobulin Receptor(Pigr) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (19-771) |
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| Oryctolagus cuniculus (Rabbit) | RFL32804OF | Recombinant Full Length Rabbit Polymeric Immunoglobulin Receptor(Pigr) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (19-773) |
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| Rattus norvegicus (Rat) | RFL27254RF | Recombinant Full Length Rat Polymeric Immunoglobulin Receptor(Pigr) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (19-769) |
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| Zebrafish | PIGR-8496Z | Recombinant Zebrafish PIGR | Mammalian Cell | His |
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| Chicken | PIGR-3436C | Recombinant Chicken PIGR | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- PIGR Related Articles
PIGR involved in several pathways and played different roles in them. We selected most pathways PIGR participated on our site, such as Intestinal i, ne network for IgA production, which may be useful for your reference. Also, other proteins which involved in the same pathway with PIGR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Intestinal i | HLA-DPA1;Il2;IL-15RA;CCL25B;TNFRSF13B;HLA-DQA2;HLA-DMA;CCL27B;HLA-DRA |
| ne network for IgA production | BMA1;HLA-DPA1;HLA-DMB;ITGB7;IL6;MHC2DEB;HLA-DRB3;Icosl;HLA-DRB4 |
PIGR has several biochemical functions, for example, polymeric immunoglobulin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PIGR itself. We selected most functions PIGR had, and list some proteins which have the same functions with PIGR. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| polymeric immunoglobulin receptor activity |
PIGR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PIGR here. Most of them are supplied by our site. Hope this information will be useful for your research of PIGR.
SGK1; Dynll1; MIS12; cona_canen; CDK6; STK4
Kaetzel, CS; et al. Cooperativity among secretory IgA, the polymeric immunoglobulin receptor, and the gut microbiota promotes host-microbial mutualism. IMMUNOLOGY LETTERS 162:10-21(2014).
Armitage, CW; O'Meara, CP; et al. Evaluation of intra- and extra-epithelial secretory IgA in chlamydial infections. IMMUNOLOGY 143:520-530(2014).
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