PIK3C2G
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Official Full Name
phosphoinositide-3-kinase, class 2, gamma polypeptide
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Overview
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The biological function of this gene has not yet been determined. -
Synonyms
PIK3C2G; phosphoinositide-3-kinase, class 2, gamma polypeptide; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma; PI3K-C2-gamma; PTDINS-3-kinase C2 gamma; ptdIns-3-kinase C2 subunit gamma; phosphoinositide 3-kinase-C2-gamma; ph;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Human
- Mouse
- Rat
- E.coli
- HEK293
- Insect Cell
- Mammalian Cell
- Sf21
- Sf9 Insect Cell
- GST
- His
- Fc
- Avi
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | PIK3C2G-1453H | Active Recombinant Human PIK3C2G, GST-tagged | Sf9 Insect Cell | GST | 468-1203 aa |
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| Human | PIK3C2G-165H | Active Recombinant Human PIK3C2G protein, GST-tagged | Insect Cell | GST | 468-1203 |
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| Human | PIK3C2G-192H | Active Recombinant Human PIK3C2G(468-1203) Protein, N-GST-tagged | Sf21 | GST | 468-1203 aa |
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| Human | PIK3C2G-2672H | Recombinant Human PIK3C2G protein, His-tagged | E.coli | His | 11-336 aa | |
| Mouse | PIK3C2G-12799M | Recombinant Mouse PIK3C2G Protein | Mammalian Cell | His |
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| Mouse | PIK3C2G-6735M | Recombinant Mouse PIK3C2G Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi |
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| Mouse | PIK3C2G-6735M-B | Recombinant Mouse PIK3C2G Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | PIK3C2G-4459R | Recombinant Rat PIK3C2G Protein | Mammalian Cell | His |
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| Rat | PIK3C2G-4119R | Recombinant Rat PIK3C2G Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi |
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| Rat | PIK3C2G-4119R-B | Recombinant Rat PIK3C2G Protein Pre-coupled Magnetic Beads | HEK293 |
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- Involved Pathway
- Protein Function
- Interacting Protein
PIK3C2G involved in several pathways and played different roles in them. We selected most pathways PIK3C2G participated on our site, such as Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with PIK3C2G were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Inositol phosphate metabolism | PIP5K2;INPP5L;CDIPT;PLCG1;PLCD1;PIP4K2B;PIP5KL1;PI4KB;PLCD3A |
| Metabolic pathways | AGL;POLG;SAT1;PGAM2;ADI1;SAT2B;MCEE;ADH2-2;PAPSS2A |
| Phosphatidylinositol signaling system | IPMK;PTENB;TMEM55A;CDS1;PIK3R5;DGKAA;PIP5K1BA;MTMR1B;PIKFYVE |
PIK3C2G has several biochemical functions, for example, 1-phosphatidylinositol-3-kinase activity, 1-phosphatidylinositol-4-phosphate 3-kinase activity, ATP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PIK3C2G itself. We selected most functions PIK3C2G had, and list some proteins which have the same functions with PIK3C2G. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 1-phosphatidylinositol-3-kinase activity | PIK3CG;PIK3C3;ATM;PIK3C2G;PIK3C2B;PIK3CA;PIK3C2A;PIK3CB;PIK3CD |
| 1-phosphatidylinositol-4-phosphate 3-kinase activity | PIK3CD;PIK3CA;PIK3C2G;PIK3CG;PIK3C2B;PIK3CB;PIK3C2A |
| ATP binding | CIT;HSPA2;IFIH1;CKMT1B;BRIP1;SRPK1A;PCXB;DHX58;ABCC8 |
| phosphatidylinositol binding | SNX10A;PIK3C2B;MTM1;SH3PXD2A;SNX29;AKR1C1;FCHO2;SNX2;SNX16 |
| phosphatidylinositol phosphate kinase activity | PIP5K1BB;PIK3C2G;PIP5K1AA;PIP5K1BA;PIP5K1AB;PIP5K2 |
PIK3C2G has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PIK3C2G here. Most of them are supplied by our site. Hope this information will be useful for your research of PIK3C2G.
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