PIK3R4

  • Official Full Name

    phosphoinositide-3-kinase, regulatory subunit 4

  • Overview

    Phosphoinositide 3-kinase regulatory subunit 4, also known as PI3-kinase regulatory subunit 4 or PI3-kinase p150 subunit or phosphoinositide 3-kinase adaptor protein, or VPS15 is an enzyme that in humans is encoded by the PIK3R4 gene.
  • Synonyms

    PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4; phosphoinositide 3-kinase regulatory subunit 4; p150; VPS15; PI3-kinase p150 subunit; PI3-kinase regulatory subunit 4; phosphoinositide 3-kinase adaptor protein; phosphatidylinositol 3-kinase-associ;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PIK3R4-1719H Recombinant Human PIK3R4, His-tagged E.coli His 1-330aa
Human PIK3R4-3183HCL Recombinant Human PIK3R4 293 Cell Lysate HEK293 N/A
Human PIK3R4-1245H Recombinant Human PIK3R4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse PIK3R4-12809M Recombinant Mouse PIK3R4 Protein Mammalian Cell His
Mouse PIK3R4-6741M Recombinant Mouse PIK3R4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse PIK3R4-6741M-B Recombinant Mouse PIK3R4 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

PIK3R4 involved in several pathways and played different roles in them. We selected most pathways PIK3R4 participated on our site, such as Regulation of autophagy, which may be useful for your reference. Also, other proteins which involved in the same pathway with PIK3R4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Regulation of autophagyIFNA8;GABARAPL1;PRKAA2;ATG13;GABARAP;ATG4C;INS1;IFNA17;ATG3

PIK3R4 has several biochemical functions, for example, ATP binding, protein binding, protein kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PIK3R4 itself. We selected most functions PIK3R4 had, and list some proteins which have the same functions with PIK3R4. You can find most of the proteins on our site.

Function Related Protein
ATP bindingSLK;LARS;LCK;LTK;PIK3C2A;MCCC2;NTRK2;GRK1B;DDX39AA
protein bindingTTC39B;AMBRA1;SIK2;ZDHHC17;PRICKLE1A;FRMPD2;WFS1;TSN;ATP5F1
protein kinase activityCAMKK1A;ABL1;PAK1;RPS6KA6;STK3;TEX14;EK1;MAP3K2;AKT2L
protein serine/threonine kinase activityRPS6KA1;AKT1;PLK2B;RIOK3;SIK3;LMTK2;CDK15;MAP4K6;AKT3

PIK3R4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PIK3R4 here. Most of them are supplied by our site. Hope this information will be useful for your research of PIK3R4.

ATG14; NRBF2; BECN1

Research Area

Related articles

Ni, Y; Sinnett-Smith, J; et al. PKD1 Mediates Negative Feedback of PI3K/Akt Activation in Response to G Protein-Coupled Receptors. PLOS ONE 8:-(2013).
Feola, A; Cimini, A; et al. The Inhibition of p85 alpha PI3KSer83 Phosphorylation Prevents Cell Proliferation and Invasion in Prostate Cancer Cells. JOURNAL OF CELLULAR BIOCHEMISTRY 114:2114-2119(2013).
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