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PIWIL1

  • Official Full Name

    piwi-like RNA-mediated gene silencing 1

  • Overview

    This gene encodes a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. The encoded protein may play a role as an intrinsic regulator of the self-renewal capacity of germline and hematopoietic stem cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
  • Synonyms

    PIWIL1; piwi-like RNA-mediated gene silencing 1; HIWI; MIWI; PIWI; CT80.1; piwi-like protein 1; piwi homolog;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PIWIL1-33H Recombinant Human PIWIL1 Protein, GST-tagged Wheat Germ GST
Human PIWIL1-1736H Recombinant Human PIWIL1, His-tagged E.coli His N-term-350aa
Human PIWIL1-1359HCL Recombinant Human PIWIL1 cell lysate N/A
Mouse PIWIL1-12852M Recombinant Mouse PIWIL1 Protein Mammalian Cell His
Mouse PIWIL1-6772M Recombinant Mouse PIWIL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse PIWIL1-6772M-B Recombinant Mouse PIWIL1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque PIWIL1-3443R Recombinant Rhesus monkey PIWIL1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque PIWIL1-3261R Recombinant Rhesus Macaque PIWIL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque PIWIL1-3261R-B Recombinant Rhesus Macaque PIWIL1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish PIWIL1-9698Z Recombinant Zebrafish PIWIL1 Mammalian Cell His
Chicken PIWIL1-3714C Recombinant Chicken PIWIL1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PIWIL1 Related Research Area

PIWIL1 involved in several pathways and played different roles in them. We selected most pathways PIWIL1 participated on our site, such as Dorso-ventral axis formation, which may be useful for your reference. Also, other proteins which involved in the same pathway with PIWIL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Dorso-ventral axis formationMAP2K1;CPEB2;CPEB3;ETV7;SOS1;PPP1R2P9;ETS1;GRB2A;GRB2B

PIWIL1 has several biochemical functions, for example, mRNA binding, piRNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PIWIL1 itself. We selected most functions PIWIL1 had, and list some proteins which have the same functions with PIWIL1. You can find most of the proteins on our site.

Function Related Protein
mRNA bindingPCBP1;ZFP36;RPL7;D19BWG1357E;CROP;RBM4;TYMS;NCBP2;C1QBP
piRNA bindingPIWIL1;PIWIL2;PIWIL4
protein bindingTRIP12;PDE4D;DAAM1;MTAP1B;DOHH;UHRF2;MRPS27;HIST1H3C;DYSFIP1
protein kinase bindingGRB2;KIF20A;MAP2K3;PKD1;PFKFB2;SREBF1;CADPS;RPS6KA3;STAP1
single-stranded RNA bindingDHX58;ANXA1;CBX6;IFIH1;AGO2;PIWIL1;LUZP4;EIF2C3;LSM14A

PIWIL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PIWIL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PIWIL1.

DICER1; b4dyc6_human; HSP90AA1; HSF2; FKBP5; PTGES3; HSP90AB1; NUDCD3; q96be0_human; PPP5C; CACYBP; NUDC

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