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PKNOX1

Official Full Name

PBX/knotted 1 homeobox 1
Overview

Homeobox protein PKNOX1 is a protein that in humans is encoded by the PKNOX1 gene.
Synonyms

PKNOX1; PBX/knotted 1 homeobox 1; homeobox protein PKNOX1; PREP1; human homeobox containing protein; Pbx regulating protein 1; PBX/knotted homeobox 1; homeobox protein PREP-1; Pbx regulating protein-1; human homeobox-containing protein; pkonx1c;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rhesus Macaque

Source

E.coli
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PKNOX1-208H	Recombinant Human PKNOX1, His-tagged	E.coli	His	1-436aa	Inquiry
Human	PKNOX1-3148HCL	Recombinant Human PKNOX1 293 Cell Lysate	HEK293	N/A		Inquiry
Mouse	PKNOX1-12876M	Recombinant Mouse PKNOX1 Protein	Mammalian Cell	His		Inquiry
Mouse	PKNOX1-6789M	Recombinant Mouse PKNOX1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	PKNOX1-6789M-B	Recombinant Mouse PKNOX1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	PKNOX1-3450R	Recombinant Rhesus monkey PKNOX1 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	PKNOX1-3268R-B	Recombinant Rhesus Macaque PKNOX1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	PKNOX1-3268R	Recombinant Rhesus Macaque PKNOX1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein
PKNOX1 Related Articles

PKNOX1 involved in several pathways and played different roles in them. We selected most pathways PKNOX1 participated on our site, such as SIDS Susceptibility Pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PKNOX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
SIDS Susceptibility Pathways	MECP2;POU3F2;LMX1B;PLP1;KCNH2;SST;DEAF1;GATA2;KCNQ1

PKNOX1 has several biochemical functions, for example, protein heterodimerization activity, sequence-specific DNA binding, transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PKNOX1 itself. We selected most functions PKNOX1 had, and list some proteins which have the same functions with PKNOX1. You can find most of the proteins on our site.

Function	Related Protein
protein heterodimerization activity	CHRNA5;BMP6;HIST1H2BM;ZHX3;LIMK2;H2-AA;TAS1R3;ABTB2;SRI
sequence-specific DNA binding	NR6A1A;DBPB;NKX6-1;HOXB4A;RERE;DLX3;FOXJ2;NR1H4;DMRT2
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding	FOXF2A;BHLHE40;CEBPB;USF2;ATF2;NKX2-1;SOX10;T;SNAI2
transcription factor activity, sequence-specific DNA binding	NR2F1A;ZNF567;FOXF2A;SREBF1;TARDBP;BLZF1;CNOT7;KAT7A;MYC
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	SLAMF7;FOXF2;ATF3;MAFG;BARX1;BARHL1A;MYF6;PAX9;SOX17

PKNOX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PKNOX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PKNOX1.

PBX2; pp2_dna; MEIS2; PBX1; PBX1; PBX3; q9wmx2-pro_0000037548; mdm2_human_probe; Pbx2; Actb; Pbx1; Mybbp1a

Tomoeda, M; Yuki, M; et al. Role of Meis1 in mitochondrial gene transcription of pancreatic cancer cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 410:798-802(2011).

Tran, S; Lamba, P; et al. SMADs and FOXL2 Synergistically Regulate Murine FSH beta Transcription Via a Conserved Proximal Promoter Element. MOLECULAR ENDOCRINOLOGY 25:1170-1183(2011).