PLCB1

  • Official Full Name

    Plcb1 phospholipase C, beta 1
  • Synonyms

    PLCB1;phospholipase C, beta 1;1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1;PLC-154;PLC-beta-1;phospholipase C-beta-1;phospholipase C-beta-1a;phosphoinositide phospholipase C;phosphoinositide phospholipase C-beta-1;1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1;Plcb;AI132408;mKIAA0581;3110043I21Rik

Recombinant Proteins

  • Rhesus macaque
  • Rat
  • Human
  • Mouse
  • Mammalian Cells
  • E.coli
  • HEK293
  • His
  • T7
  • Non
  • Avi
  • Fc
  • Flag
  • DDK
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
PLCB1-3461R Recombinant Rhesus monkey PLCB1 Protein, His-tagged Mammalian Cells Rhesus macaque His
PLCB1-4499R Recombinant Rat PLCB1 Protein Mammalian Cells Rat His
PLCB1-7157H Recombinant Human PLCB1 protein, His & T7-tagged E.coli Human His&T7 Glu316~Gly476
PLCB1-831H Recombinant Human PLCB1 Mammalian Cells Human His
PLCB1-3131HCL Recombinant Human PLCB1 293 Cell Lysate HEK293 Human Non
PLCB1-1702H Recombinant Human PLCB1 Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
PLCB1-1702H-B Recombinant Human PLCB1 Protein Pre-coupled Magnetic Beads HEK293 Human
PLCB1-1803HFL Recombinant Full Length Human PLCB1 Protein, C-Flag-tagged Mammalian Cells Human Flag Full L.
PLCB1-3279R Recombinant Rhesus Macaque PLCB1 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
PLCB1-3279R-B Recombinant Rhesus Macaque PLCB1 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
PLCB1-4139H Recombinant Human PLCB1 Protein (Lys27-Met245), N-His tagged E.coli Human His Lys27-Met245
PLCB1-4159R Recombinant Rat PLCB1 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
PLCB1-4159R-B Recombinant Rat PLCB1 Protein Pre-coupled Magnetic Beads HEK293 Rat
Plcb1-4913M Recombinant Mouse Plcb1 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
PLCB1-5315H Recombinant Human PLCB1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc

    Involved Pathway

    PLCB1 involved in several pathways and played different roles in them. We selected most pathways PLCB1 participated on our site, such as Inositol phosphate metabolism,Metabolic pathways,Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLCB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Pancreatic secretion GNAS,CLCA2,GNAQ,PLA2G10,CELA2B,PLA2G1B,ATP1A2,PLCB3,PRSS2,CLCA1
    Huntingtons disease COX5B,ATP5B,POLR2D,COX7B,NDUFA3,NDUFV1,TBPL2,NDUFA6,POLR2H,NDUFS8
    Sphingolipid signaling pathway PPP2R5A,PPP2R2B,PRKCZ,PPP2CB,S1PR2,PPP2R2C,ABCC1,LASS4,LOC100328615,TP53
    Wnt signaling pathway WNT4A,CAMK2G1,GSK3AA,CCND2A,RAC3,RUVBL1,PPP3CCA,NLK,CHD8,CAMK2B
    Adrenergic signaling in cardiomyocytes TPM4B,MAPK14B,GNAI1,ACTC1A,PRKACAB,PIK3R2,CACNA2D3,CACNG3,AGTR1B,CACNG1A
    Long-term potentiation GRM1,KRAS,PPP1R1A,MAPK3,PLCB2,CALM3,CAMK2D,GNAQ,RPS6KA2,PRKCB
    Estrogen signaling pathway CALM3,PIK3CD,GNAI3,KRAS,GNAI2,CREB3L3,CALM2,KCNJ5,AKT1,PIK3R5
    Amoebiasis SERPINB3,PLCB3,Casp3,TLR2,IL12B,SERPINB4,IL6,GNAL,RAB7A,PRKACA
    Cholinergic synapse FYN,GNG11,CHRNA7,MAPK3,GNA11,KCNJ4,GNG10,CREB3L1,KCNJ12,ACHE

    Protein Function

    PLCB1 has several biochemical functions, for example, GTPase activator activity,calcium ion binding,calmodulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PLCB1 itself. We selected most functions PLCB1 had, and list some proteins which have the same functions with PLCB1. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding NOTCH2,VLDLR,FKBP9,SNCB,NKD2A,TTYH1,SPNA1,FBN2,CAPN1,CANX
    calmodulin binding MAPKAPK2B,CAMK2G,MYH10,KCNQ3,CNGA2,DAPK1,RRAD,MYO5C,MYH13,MIP
    signal transducer activity CXCR3.1,OLFR50,RGS9A,TAAR12F,BST2,NPFFR1L3,TAS2R108,TAAR10,GPR139,CD24
    phosphatidylinositol-4,5-bisphosphate binding FAM123B,Apba1,KLHL8,ANXA8,FAM123A,SNX20,STXBP6,EXOC1,PARD3,VIL1
    enzyme binding RPA3,CYP2C19,PLCE1,ATXN10,RCOR1,MLEC,KALRN,TAL1,CCND1,KDM1A
    protein binding PDE6H,PSMA6,ATP7B,PTCH1,BCDIN3D,EIF1AD,HIST1H2AG,CD200R4,DNM3,EDDM3B
    lamin binding SUN2,TMPO,SUN1,PKP1,TMEM201,PPP4C,LBR,BNIP3L,IFI27,NARF
    protein homodimerization activity BMP4,HPRT1,CADM1B,USF2,IL6ST,HMOX1,MCL1B,HNF4A,BNIP3,UGT1A7
    GTPase activator activity TBC1D16,ACAP1,TBC1D7,RGS9A,ARHGAP8,ARRB1,ARHGEF19,CDC42EP2,ARHGAP33,ARFGAP2

    Interacting Protein

    PLCB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLCB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLCB1.

    CTBP2;TFCP2;CTBP1;CTBP2;CEP76;SPTBN1

    PLCB1 Related Signal Pathway

    Resources

    References

    • Ichishima, K; Yamamoto, S; et al. alpha(1)-Adrenoceptor-mediated depletion of phosphatidylinositol 4, 5-bisphosphate inhibits activation of volume-regulated anion channels in mouse ventricular myocytes. BRITISH JOURNAL OF PHARMACOLOGY 161:193-206(2010).
    • Lo Vasco, VR; Fabrizi, C; et al. Expression of phosphoinositide-specific phospholipase C isoenzymes in cultured astrocytes. JOURNAL OF CELLULAR BIOCHEMISTRY 100:952-959(2007).

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