| Description : |
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
133.5 kDa |
| AA Sequence : |
MAGAQPGVHALQLKPVCVSDSLKKG TKFVKWDDDSTIVTPIILRTDPQGF FFYWTDQNKETELLDLSLVKDARCG RHAKAPKDPKLRELLDVGNIGRLEQ RMITVVYGPDLVNISHLNLVAFQEE VAKEWTNEVFSLATNLLAQNMSRDA FLEKAYTKLKLQVTPEGRIPLKNIY RLFSADRKRVETALEACSLPSSRND SIPQEDFTPEVYRVFLNNLCPRPEI DNIFSEFGAKSKPYLTVDQMMDFIN LKQRDPRLNEILYPPLKQEQVQVLI EKYEPNNSLARKGQISVDGFMRYLS GEENGVVSPEKLDLNEDMSQPLSHY FINSSHNTYLTAGQLAGNSSVEMYR QVLLSGCRCVELDCWKGRTAEEEPV ITHGFTMTTEISFKEVIEAIAECAF KTSPFPILLSFENHVDSPKQQAKMA EYCRLIFGDALLMEPLEKYPLESGV PLPSPMDLMYKILVKNKKKSHKSSE GSGKKKLSEQASNTYSDSSSMFEPS SPGAGEADTESDDDDDDDDCKKSSM DEGTAGSEAMATEEMSNLVNYIQPV KFESFEISKKRNKSFEMSSFVETKG LEQLTKSPVEFVEYNKMQLSRIYPK GTRVDSSNYMPQLFWNAGCQMVALN FQTMDLAMQINMGMYEYNGKSGYRL KPEFMRRPDKHFDPFTEGIVDGIVA NTLSVKIISGQFLSDKKVGTYVEVD MFGLPVDTRRKAFKTKTSQGNAVNP VWEEEPIVFKKVVLPTLACLRIAVY EEGGKFIGHRILPVQAIRPGYHYIC LRNERNQPLTLPAVFVYIEVKDYVP DTYADVIEALSNPIRYVNLMEQRAK QLAALTLEDEEEVKKEADPGETPSE APSEARTTPAENGVNHTTTLTPKPP SQALHSQPAPGSVKAPAKTEDLIQS VLTEVEAQTIEELKQQKSFVKLQKK HYKEMKDLVKRHHKKTTDLIKEHTT KYNEIQNDYLRRRAALEKSAKKDSK KKSEPSSPDHGSSTIEQDLAALDAE MTQKLIDLKDKQQQQLLNLRQEQYY SEKYQKREHIKLLIQKLTDVAEECQ NNQLKKLKEICEKEKKELKKKMDKK RQEKITEAKSKDKSQMEEEKTEMIR SYIQEVVQYIKRLEEAQSKRQEKLV EKHKEIRQQILDEKPKGEGSSSFLS ETCHEDPSVSPNFTPPNPQALKWTR TRPLEQKLISEEDLAANDILDYKDD DDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
