|Official Full Name||perilipin 2|
|Background||The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene.|
|Synonyms||PLIN2; perilipin 2; ADFP; ADRP; adipose differentiation-related protein; adipophilin; Perilipin-2; Adipophilin; Adipose differentiation-related protein; perilipin-2; MGC1059; OTTHUMP00000021107|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
plin2 involved in several pathways and played different roles in them. We selected most pathways plin2 participated on our site, such as Adipogenesis, Fatty acid, triacylglycerol, and ketone body metabolism, HIF-1-alpha transcription factor network, which may be useful for your reference. Also, other proteins which involved in the same pathway with plin2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Adipogenesis||AGT; CREB1; DLK1; MEF2B; GATA2; CTNNB1; CDKN1A; KLF5; EGR2B; CEBPA|
|Fatty acid, triacylglycerol, and ketone body metabolism||MED16; CPT1B; MED20; SLC25A1A; ACOT11A; G0S2; CYP4A11; ACOT2; AGPAT1; CDK8|
|HIF-1-alpha transcription factor network||ENG; EGLN3; GATA2; ADM; COPS5; CP; TFF3; NPM1; NDRG1; CITED2|
|Metabolism||AADAC; TM9SF1; GYG1B; MMS19; NUDT4A; B3GNT2A; ATP5S; PYGMB; CDK19; APOEB|
|Metabolism of lipids and lipoproteins||VAPB; Agmo; APOA5; APOEA; PHOSPHO1; CYP2Y3; LBR; BCHE; PPM1LA; DPEP1|
|PPARA activates gene expression||MED20; MED18; MED19; GRHL1; MED7; MTF1; MED23; MED22; MED9; TIAM2|
|Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)||MED21; MED26; MED22; MED6; MED10; GLIPR1; MED7; MED31; MED29; MED15|
plin2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by plin2 itself. We selected most functions plin2 had, and list some proteins which have the same functions with plin2. You can find most of the proteins on our site.
plin2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with plin2 here. Most of them are supplied by our site. Hope this information will be useful for your research of plin2.