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Official Full Name perilipin 2
Background The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene.
Synonyms PLIN2; perilipin 2; ADFP; ADRP; adipose differentiation-related protein; adipophilin; Perilipin-2; Adipophilin; Adipose differentiation-related protein; perilipin-2; MGC1059; OTTHUMP00000021107
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ADRP-3201H Recombinant Human PLIN2 protein, His-tagged E.coli His
    Human ADRP-3207H Recombinant Human PLIN2 protein, His-tagged E.coli His
    Human PLIN2-201H Recombinant Human PLIN2, T7 tagged E.coli T7
    Human PLIN2-3014H Recombinant Human PLIN2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human PLIN2-3107HCL Recombinant Human PLIN2 293 Cell Lysate HEK293 N/A
    Human PLIN2-341H Recombinant Human PLIN2 Protein, GST-tagged Wheat Germ GST
    Human PLIN2-62H Recombinant Human Perilipin 2, T7-tagged E.coli T7
    Human PLIN2-63H Recombinant Human PLIN2, His-tagged E.coli His
    Human PLIN2-904H Recombinant Human Perilipin 2, His-tagged E.coli His
    Human PLIN2-9448H Recombinant Human PLIN2, His-tagged E.coli His
    Mouse PLIN2-12972M Recombinant Mouse PLIN2 Protein Mammalian Cell His
    Chicken PLIN2-3070C Recombinant Chicken PLIN2 Mammalian Cell His
    Zebrafish PLIN2-3342Z Recombinant Zebrafish PLIN2 Mammalian Cell His

    plin2 involved in several pathways and played different roles in them. We selected most pathways plin2 participated on our site, such as Adipogenesis, Fatty acid, triacylglycerol, and ketone body metabolism, HIF-1-alpha transcription factor network, which may be useful for your reference. Also, other proteins which involved in the same pathway with plin2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adipogenesis AGT; CREB1; DLK1; MEF2B; GATA2; CTNNB1; CDKN1A; KLF5; EGR2B; CEBPA
    Fatty acid, triacylglycerol, and ketone body metabolism MED16; CPT1B; MED20; SLC25A1A; ACOT11A; G0S2; CYP4A11; ACOT2; AGPAT1; CDK8
    HIF-1-alpha transcription factor network ENG; EGLN3; GATA2; ADM; COPS5; CP; TFF3; NPM1; NDRG1; CITED2
    Metabolism of lipids and lipoproteins VAPB; Agmo; APOA5; APOEA; PHOSPHO1; CYP2Y3; LBR; BCHE; PPM1LA; DPEP1
    PPARA activates gene expression MED20; MED18; MED19; GRHL1; MED7; MTF1; MED23; MED22; MED9; TIAM2
    Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) MED21; MED26; MED22; MED6; MED10; GLIPR1; MED7; MED31; MED29; MED15

    plin2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by plin2 itself. We selected most functions plin2 had, and list some proteins which have the same functions with plin2. You can find most of the proteins on our site.

    Function Related Protein

    plin2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with plin2 here. Most of them are supplied by our site. Hope this information will be useful for your research of plin2.

    MAPK10; ftsX

    Kimura, A; Sakurai, T; et al. Identification of Target Antigens of Antiendothelial Cell Antibodies Against Human Brain Microvascular Endothelial Cells in Healthy Subjects. CURRENT NEUROVASCULAR RESEARCH 12:25-30(2015).
    Mulay, K; White, VA; et al. Sebaceous carcinoma: clinicopathologic features and diagnostic role of immunohistochemistry (including androgen receptor). CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE 49:326-332(2014).

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