PODXL

  • Official Full Name

    podocalyxin-like

  • Overview

    This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.
  • Synonyms

    PODXL; podocalyxin-like; podocalyxin; Gp200; PC; PCLP; GCTM-2 antigen; podocalyxin-like protein 1; PCLP-1; MGC138240;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Yeast
  • DDK|His
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • His|T7
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PODXL-218H Active Recombinant Human PODXL protein, His-tagged Mammalian cells His
Human PODXL-32H Recombinant Human PODXL protein, MYC/DDK-tagged HEK293 Myc/DDK
Human PODXL-062H Recombinant Human PODXL Protein, DDK/HIS-tagged HEK293 DDK/His
Human PODXL-1823H Recombinant Human PODXL, GST-tagged E.coli GST 23-428aa
Human PODXL-7641H Recombinant Human PODXL protein, His & GST-tagged E.coli His/GST Ala220~Ile431 (Accession # O00592)
Human PODXL-063H Recombinant Human PODXL Protein, DDK/HIS-tagged HEK293 DDK/His
Human PODXL-3059HCL Recombinant Human PODXL 293 Cell Lysate HEK293 N/A
Human PODXL-0402H Recombinant Human PODXL protein, His-tagged E.coli His 23-428 aa
Human PODXL-4322H Recombinant Human PODXL protein, His-tagged E.coli His 32-458aa
Human PODXL-3885H Recombinant Human PODXL Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human PODXL-02H Recombinant Human PODXL Protein, His-tagged HEK293 His 23-429aa
Human PODXL-2605H Recombinant Human PODXL Protein, His-tagged E.coli N-His Ser23-Ala220
Human PODXL-3885H-B Recombinant Human PODXL Protein Pre-coupled Magnetic Beads HEK293
Human PODXL-1640H Recombinant Human PODXL Protein (32-458 aa), His-tagged Yeast His 32-458 aa
Mouse Podxl-7642M Recombinant Mouse Podxl protein, His & T7-tagged E.coli His/T7 Pro171~Ser404 (Accession # Q9R0M4)
Mouse Podxl-31M Recombinant Mouse Podxl Protein, His-tagged Insect Cell His
Mouse Podxl-4977M Recombinant Mouse Podxl Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Podxl-7388M Recombinant Mouse Podxl Protein, His-tagged His 22-404
Mouse Podxl-1956M Recombinant Mouse Podxl Protein, His-tagged E.coli N-His His22-Ser404
Rat Podxl-7643R Recombinant Rat Podxl protein, His & T7-tagged E.coli His/T7 Pro153~Ser386 (Accession # Q9WTQ2)
Rat PODXL-4557R Recombinant Rat PODXL Protein Mammalian Cell His
Rat PODXL-4217R Recombinant Rat PODXL Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PODXL-4217R-B Recombinant Rat PODXL Protein Pre-coupled Magnetic Beads HEK293
Rat Podxl-5829R Recombinant Rat Podxl protein, His-tagged Yeast His 25-386aa
Rat Podxl-1957R Recombinant Rat Podxl Protein, His-tagged E.coli N-His Gly408-Leu485
Zebrafish PODXL-4091Z Recombinant Zebrafish PODXL Mammalian Cell His
Chicken PODXL-4672C Recombinant Chicken PODXL Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PODXL Related Articles
  • PODXL Related Research Area

PODXL involved in several pathways and played different roles in them. We selected most pathways PODXL participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PODXL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

PODXL has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PODXL itself. We selected most functions PODXL had, and list some proteins which have the same functions with PODXL. You can find most of the proteins on our site.

Function Related Protein
protein bindingGNG5;DCTN1;PIM3;INTS12;TRAPPC3;GRM6;MBNL3;DRD2;YY1

PODXL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PODXL here. Most of them are supplied by our site. Hope this information will be useful for your research of PODXL.

IQGAP1

Kaprio, T; Fermer, C; et al. Podocalyxin is a marker of poor prognosis in colorectal cancer. BMC CANCER 14:-(2014).
Kaprio, T; Hagstrom, J; et al. A comparative study of two PODXL antibodies in 840 colorectal cancer patients. BMC CANCER 14:-(2014).
  • Q&As
  • Reviews

Q&As (5)

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How does PODXL contribute to cancer metastasis? 02/09/2022

PODXL promotes cancer cell migration and invasion, facilitating the spread of cancer to distant organs and tissues.

Can PODXL be detected in circulating tumor cells (CTCs)? 07/26/2021

Yes, PODXL expression in CTCs can be a valuable biomarker for monitoring cancer progression and treatment response.

Are there ongoing clinical trials targeting PODXL in cancer therapy? 02/17/2021

Yes, several clinical trials are investigating the efficacy of drugs targeting PODXL as a novel approach in cancer treatment.

Are there therapeutic implications for targeting PODXL in cancer treatment? 03/22/2019

Yes, targeting PODXL is being explored as a potential therapeutic strategy to inhibit cancer progression and metastasis.

Can PODXL be used for prognosis in cancer patients? 04/03/2016

Elevated PODXL expression is often associated with poor prognosis in cancer patients, indicating a more aggressive disease course.

Customer Reviews (3)

Write a review
Reviews
03/22/2023

    Manufacturers may offer the option for custom protein production.

    02/26/2023

      They can assist in identifying the most suitable experimental protocols or provide recommendations for optimal usage.

      07/24/2017

        Manufacturers can provide researchers with purified and validated ARL5B protein, ensuring its quality and reliability for use in experiments and trials.

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