Recombinant Mouse Podxl Protein, Myc/DDK-tagged
Cat.No. : | Podxl-4977M |
Product Overview : | Purified recombinant protein of mouse full-length podocalyxin-like (Podxl), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 53.8 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Podxl podocalyxin-like [ Mus musculus (house mouse) ] |
Official Symbol : | Podxl |
Synonyms : | PODXL; podocalyxin-like; podocalyxin; podocalyxin-like protein 1; PC; Ly102; Pclp1; PCLP-1; AW121214 |
Gene ID : | 27205 |
mRNA Refseq : | NM_013723 |
Protein Refseq : | NP_038751 |
UniProt ID : | Q9R0M4 |
Products Types
◆ Recombinant Protein | ||
PODXL-1640H | Recombinant Human PODXL Protein (32-458 aa), His-tagged | +Inquiry |
Podxl-1957R | Recombinant Rat Podxl Protein, His-tagged | +Inquiry |
PODXL-4217R | Recombinant Rat PODXL Protein, His (Fc)-Avi-tagged | +Inquiry |
PODXL-2605H | Recombinant Human PODXL Protein, His-tagged | +Inquiry |
PODXL-3885H | Recombinant Human PODXL Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PODXL-3059HCL | Recombinant Human PODXL 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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