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POP1

Official Full Name

processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
Overview

This gene encodes the protein subunit of two different small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is a ribonuclease that localizes to the nucleus and functions in pre-RNA processing. This protein is also an autoantigen in patients suffering from connective tissue diseases. Alternative splicing results in multiple transcript variants.
Synonyms

POP1; processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae); ribonucleases P/MRP protein subunit POP1; processing of precursors 1; KIAA0061; MGC17365; 4932434G09Rik; hPOP1; MGC36536; POP1_HUMAN; Processing of precursor 1; Ribonucleases P/MRP protein subunit homolog;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	POP1-3012HCL	Recombinant Human POP1 293 Cell Lysate	HEK293	N/A		Inquiry

Involved Pathway
Protein Function
Interacting Protein
POP1 Related Research Area

POP1 involved in several pathways and played different roles in them. We selected most pathways POP1 participated on our site, such as Gene Expression, RNA transport, Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with POP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Gene Expression	HNRNPH2;GM3258;ZNF443;HIPK1;TRDMT1;RPP38;ZNF710;YBX1;ZNF566
RNA transport	NXT2;SMN1;THOC1;GEMIN6;EIF1;EIF3G;EIF4BB;KPNB1;EIF4A1B
Ribosome biogenesis in eukaryotes	NHP2L1;NHP2L1B;RNASEN;NMD3;EMG1;NOP56;BMS1;UTP6;ACK2
tRNA processing	OSGEP;XPOT;TRMT61A;LCMT2;TRMT6;TYW5;NSUN2;TSEN2;TRMT112
tRNA processing in the nucleus	C22orf28;RPP40;ZBTB8OS;POP7;RPP30;TSEN34;FAM98B;POP1;POP4

POP1 has several biochemical functions, for example, poly(A) RNA binding, protein binding, ribonuclease MRP activity. Some of the functions are cooperated with other proteins, some of the functions could acted by POP1 itself. We selected most functions POP1 had, and list some proteins which have the same functions with POP1. You can find most of the proteins on our site.

Function	Related Protein
poly(A) RNA binding	HIST1H1C;CLNS1A;HERC5;CCDC124;WDR6;EXOSC8;ADD1;LGALS1;SFRS9
protein binding	CD84;PAK2;KCNJ5;RAD54L;EPB41B;CLSTN2;PRH2;FBN2;NTN1
ribonuclease MRP activity
ribonuclease P activity	RPP14;RPP25;RPP38;RPP30;RPP40;POP4;POP1;POP7;POP5

POP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of POP1.

RPP40; POP4; Ybx1; RPP38; POP5; Haus8; RPP25; ssrna_ug; Srp72; NOP56; ESR1; EGR1; RPL10; MNDA; HNRNPU

Inflammasome