POP1

  • Official Full Name

    processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)

  • Overview

    This gene encodes the protein subunit of two different small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is a ribonuclease that localizes to the nucleus and functions in pre-RNA processing. This protein is also an autoantigen in patients suffering from connective tissue diseases. Alternative splicing results in multiple transcript variants.

  • Synonyms

    POP1;processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae);ribonucleases P/MRP protein subunit POP1;processing of precursors 1;KIAA0061;MGC17365;4932434G09Rik;hPOP1;MGC36536;POP1_HUMAN;Processing of precursor 1;Ribonucleases P/MRP protein subunit homolog
Cat.# Product name Source (Host) Species Tag Protein Length Price
POP1-3012HCL Recombinant Human POP1 293 Cell Lysate HEK293 Human Non

    Involved Pathway

    POP1 involved in several pathways and played different roles in them. We selected most pathways POP1 participated on our site, such as Gene Expression,RNA transport,Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with POP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Gene Expression ZNF200,POLRMT,ZNF490,ZNF615,SETA,ZNF43,ESRRGA,HNRNPA0A,SPCS3,ZFP36L1B
    tRNA processing NSUN2,TSEN2,POP4,ADAT3,LCMT2,TRMT112,LAGE3,TRDMT1,XPOT,TYW1
    RNA transport NCBP2,EIF2S3Y,PEAK1,EIF4EBP2,GEMIN7,EIF4E2RS1,EEF1A1B,CASC3,THOC1,WIBG
    Ribosome biogenesis in eukaryotes RPP25L,RCL1,POP7,NHP2,WDR36,XRN2,GTPBP4,UTP14A,LSG1,LOC81691
    tRNA processing in the nucleus POP4,TSEN34,ELAC2,RPP30,XPOT,ZBTB8OS,RPP14,RPP40,POP7,TSEN54

    Protein Function

    POP1 has several biochemical functions, for example, poly(A) RNA binding,protein binding,ribonuclease MRP activity. Some of the functions are cooperated with other proteins, some of the functions could acted by POP1 itself. We selected most functions POP1 had, and list some proteins which have the same functions with POP1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding SCMH1,CDX4,KRAS,ARMCX5,EIF5A2,ACACB,LINGO1B,PKHD1L1,KDM6B,COPS7B
    ribonuclease P activity RPP38,RPP25,POP4,RPP40,POP7,RPP14,RPP30,POP5
    poly(A) RNA binding DMGDH,TRIM28,SREK1,MRPS14,SSBP1,RPS7,CRNKL1,PDAP1,SRP54A,UBE2O

    Interacting Protein

    POP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of POP1.

    RPP40;POP4;Ybx1;RPP38;POP5;Haus8;RPP25;ssrna_ug;Srp72;NOP56;ESR1;EGR1;RPL10;MNDA;HNRNPU

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