POP1

  • Official Full Name

    processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)

  • Overview

    This gene encodes the protein subunit of two different small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is a ribonuclease that localizes to the nucleus and functions in pre-RNA processing. This protein is also an autoantigen in patients suffering from connective tissue diseases. Alternative splicing results in multiple transcript variants.

  • Synonyms

    POP1;processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae);ribonucleases P/MRP protein subunit POP1;processing of precursors 1;KIAA0061;MGC17365;4932434G09Rik;hPOP1;MGC36536;POP1_HUMAN;Processing of precursor 1;Ribonucleases P/MRP protein subunit homolog
Cat.# Product name Source (Host) Species Tag Protein Length Price
POP1-3012HCL Recombinant Human POP1 293 Cell Lysate HEK293 Human Non

    Involved Pathway

    POP1 involved in several pathways and played different roles in them. We selected most pathways POP1 participated on our site, such as Gene Expression,RNA transport,Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with POP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    tRNA processing in the nucleus C2orf49,ZBTB8OS,XPOT,TSEN34,RPP40,RPP38,POP4,FAM98B,ELAC2,TSEN54
    Ribosome biogenesis in eukaryotes NVL,NXF3,XPO1,NOP10,NOP56,EMG1,NOP58,FBLL1,DKC1,cka2
    Gene Expression EIF1AXA,THOC4,HNRNPUL1,CTDP1,MED20,ZNF189,RBM5,NR2F1A,ZNF484,DGCR8
    RNA transport RPP21,THOC3,PHAX,PEAK1,EIF4A1B,NUP107,EIF4E2,KPNB1,SUMO3,THOC4
    tRNA processing TRMT12,RPP38,TYW5,QTRTD1,LCMT2,NSUN2,TRDMT1,TRMT112,WDR4,TYW3

    Protein Function

    POP1 has several biochemical functions, for example, poly(A) RNA binding,protein binding,ribonuclease MRP activity. Some of the functions are cooperated with other proteins, some of the functions could acted by POP1 itself. We selected most functions POP1 had, and list some proteins which have the same functions with POP1. You can find most of the proteins on our site.

    Function Related Protein
    ribonuclease P activity POP7,RPP38,RPP40,POP4,RPP30,POP5,RPP14,RPP25
    poly(A) RNA binding NOVA2,ZFP579,DYNC1LI1,RPL15,MRPS9,SNRNP40,MYBBP1A,EIF2S2,TIA1,GM5506
    protein binding BRAT1,NPPB,ING2,TMEM106C,GALT,AICDA,SGK3,ERO1LB,UNC45A,C14orf104

    Interacting Protein

    POP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of POP1.

    RPP40;POP4;Ybx1;RPP38;POP5;Haus8;RPP25;ssrna_ug;Srp72;NOP56;ESR1;EGR1;RPL10;MNDA;HNRNPU

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