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POU4F2

Official Full Name

POU class 4 homeobox 2
Overview

The protein encoded by this gene is a member of the POU-domain transcription factor family and may be involved in maintaining visual system neurons in the retina. The level of the encoded protein is also elevated in a majority of breast cancers, resulting in accelerated tumor growth.
Synonyms

POU4F2; POU class 4 homeobox 2; BRN3B, POU domain class 4, transcription factor 2 , POU domain, class 4, transcription factor 2; POU domain, class 4, transcription factor 2; Brn 3b; BRN3B; Brain-specific homeobox/POU domain protein 3B; Brn-3B; POU domain class 4 transcription factor 2; brain-3B; OTTHUMP00000221146; POU domain protein; Brn3b POU domain transcription factor; BRN3.2;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

C
Myc
DDK
His
His (Fc)
Avi
His|Myc
Myc|DDK

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	POU4F2-2604H	Recombinant Human POU4F2 Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	POU4F2-2672H	Recombinant Human POU4F2 Protein (1-265 aa), His-Myc-tagged	E.coli	His/Myc	1-265 aa	Inquiry
Human	POU4F2-409H	Recombinant Human POU4F2 Protein, MYC/DDK-tagged, C13 and N15-labeled	HEK293	C-Myc/DDK		Inquiry
Mouse	POU4F2-13146M	Recombinant Mouse POU4F2 Protein	Mammalian Cell	His		Inquiry
Mouse	Pou4f2-5023M	Recombinant Mouse Pou4f2 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mouse	POU4F2-6956M	Recombinant Mouse POU4F2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	POU4F2-6956M-B	Recombinant Mouse POU4F2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	POU4F2-12073Z	Recombinant Zebrafish POU4F2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

POU4F2 involved in several pathways and played different roles in them. We selected most pathways POU4F2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with POU4F2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

POU4F2 has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by POU4F2 itself. We selected most functions POU4F2 had, and list some proteins which have the same functions with POU4F2. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	ERCC6L2;HLTF;RORCB;PPARGC1A;KAT6B;ILF3B;HIST1H2BG;RBM6;ZNF668
RNA polymerase II core promoter proximal region sequence-specific DNA binding	MLXIPL;HNRNPK;ONECUT2;NKX2;POU4F2;TP73;GLI3;MIXL1;FOXK2
chromatin binding	TADA2A;KDM8;NFATC2;YAP1;EYA3;SSRP1A;LHX2;TOX;CHAF1B
sequence-specific DNA binding	IRX6;HNF1B;NKX3.2;PAX7A;E2F5;HOXD1;GATA1A;ATF5A;PAX3A
transcription factor activity, sequence-specific DNA binding	CLOCK;HNF1BA;FOXN2;FOXO3A;SIM1;ALS2CR8;ZNF577;DMRTA2;BHLHE22
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	NFAT5;MYBL2;NEUROG3;ZFP292;EHF;SOX2;CEBPZ;NFIB;MEOX1
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	NR2E1;BCL11A;KLF17;NFIL3-5;PROX2;GZF1;GATA1;HINFP;ZFPM2

POU4F2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POU4F2 here. Most of them are supplied by our site. Hope this information will be useful for your research of POU4F2.