PPAP2B
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Official Full Name
phosphatidic acid phosphatase type 2B -
Synonyms
PPAP2B;phosphatidic acid phosphatase type 2B;9229;ENSG00000162407;LPP3;VCIP;Dri42;PAP2B;1p32.2;MGC15306;lipid phosphate phosphohydrolase 3;lipid phosphate phosphohydrolase 3;PAP2 beta;phosphatidate phosphohydrolase type 2b;type-2 phosphatidic acid phosphatase-beta;vascular endothelial growth factor and type I collagen inducible;EC 3.1.3.4
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PPAP2B-28H | Recombinant Human PPAP2B, GST-tagged | Wheat Germ | Human | GST |
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| PPAP2B-3853C | Recombinant Chicken PPAP2B | Mammalian Cells | Chicken | His |
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| PPAP2B-2991HCL | Recombinant Human PPAP2B 293 Cell Lysate | HEK293 | Human | Non |
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| PPAP2B-386HF | Recombinant Full Length Human PPAP2B Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 311 amino acids |
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Involved Pathway
PPAP2B involved in several pathways and played different roles in them. We selected most pathways PPAP2B participated on our site, such as Glycerolipid metabolism,Glycerophospholipid metabolism,Ether lipid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPAP2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fc gamma R-mediated phagocytosis | PRKCG,MARCKSL1,PRKCA,RPS6KB1,PRKCD,INPP5D,GAB2,WASL,PTPRC,AKT1 |
| Ether lipid metabolism | PLA2G2A,PPAP2CB,PLA2G12B,PLA2G16,PLA2G5,PAFAH2,PLD3,UGT8A,LPCAT1,PPAP2C |
| Glycerophospholipid metabolism | PLA2G4F,DGKE,PCYT1AA,CDIPT,PCYT1A,ADPRM,LYPLA2,MBOAT2,CEPT1,AGPAT9L |
| Choline metabolism in cancer | RAC2,GPCPD1,MAP2K1,HRAS,WAS,Pdgfa&Pdgfb,PIK3CA,PDGFD,PDGFA,MTOR |
| Fat digestion and absorption | AGPAT1,LIPF,APOA1,FABP1,MOGAT3,CD36,PLA2G2D,DGAT2,PLA2G2A,SLC27A4 |
| Metabolic pathways | ACAA1,POLR2I,AGL,GUK1,QDPRB2,POC1B-GALNT4,LDHAL6B,CES1C,HYAL1,SDHD |
| Phospholipase D signaling pathway | KRAS,GRM8,ARF6,PIK3R3,PPAP2C,AGTR1B,RHEB,Kitl,SHC4,PDGFA |
| Glycerolipid metabolism | GPAT2,PPAP2C,GLYCTK,PNPLA3,DGKAA,PPAP2CB,DGAT1A,PPAP2A,DGKE,ALDH9A1 |
| Sphingolipid metabolism | OSBP,VAPB,SGPP1,ARSI,PPM1LA,CERS5,SGPL1,DEGS1,LASS1,SMPD1 |
Protein Function
PPAP2B has several biochemical functions, for example, integrin binding,lipid phosphatase activity,phosphatidate phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPAP2B itself. We selected most functions PPAP2B had, and list some proteins which have the same functions with PPAP2B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phosphatidate phosphatase activity | LPIN2,LPIN1,PPAP2C,PPAPDC1B,PPAPDC1A,PPAP2CB,STIL,LPIN3,LPPR2,LPPR3 |
| sphingosine-1-phosphate phosphatase activity | SGPP2,SGPP1 |
| phosphoprotein phosphatase activity | PPM1BA,DUSP28,PTPRUB,PPTC7A,PTPRDB,PPM1E,PTPN11B,PHPT1,PTPREB,TENC1 |
| integrin binding | ITGB6,L1CAM,WISP1,EDIL3,WISP2,TGFBI,ICAM5,P4HB,CIB2,ILK |
| protein binding | RAB33B,ARHGEF38,RBM17,PIM1,RBM23,RABAC1,VTA1,NLRP12,DPEP3,CCL28 |
| lipid phosphatase activity | LPPR3A,EPHX2,PTENA,LPPR1,PPAP2C,LPPR3,INPP5K,PPAP2D,PTENB,PPAP2A |
Interacting Protein
PPAP2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPAP2B here. Most of them are supplied by our site. Hope this information will be useful for your research of PPAP2B.
CTNND1;ITGAV;ITGA5;BCL6
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