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Official Full Name diphosphoinositol pentakisphosphate kinase 1
Background This gene encodes a dual functional inositol kinase. The encoded enzyme converts inositol hexakisphosphate to diphosphoinositol pentakisphosphate and diphosphoinositol pentakisphosphate to bis-diphosphoinositol tetrakisphosphate. This protein may be important for intracellular signaling pathways. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 15.
Synonyms PPIP5K1; diphosphoinositol pentakisphosphate kinase 1; HISPPD2A, histidine acid phosphatase domain containing 2A; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1; IPS1; KIAA0377; VIP1; IP6K; Histidine acid phosphatase domain-containing protein 2A; hsVIP1; Inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinase 1; Inositol pyrophosphate synthase 1; InsP6 and PP IP5 kinase 1; IP6 kinase; PP IP5 kinase 1; VIP1 homolog; insP6 and PP-IP5 kinase 1; histidine acid phosphatase domain containing 2A; HISPPD2A
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PPIP5K1-13788H Recombinant Human PPIP5K1, His-tagged E.coli His
    Human PPIP5K1-793HCL Recombinant Human PPIP5K1 cell lysate N/A
    Mouse PPIP5K1-13192M Recombinant Mouse PPIP5K1 Protein Mammalian Cell His

    ppip5k1 involved in several pathways and played different roles in them. We selected most pathways ppip5k1 participated on our site, such as Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with ppip5k1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Phosphatidylinositol signaling system TMEM55A; PLCB1; PIP5K1B; PRKCBB; PRKCA; INPP5J; PI4K2A; MTMR8; PIK3C2B; PIK3R5

    ppip5k1 has several biochemical functions, for example, ATP binding, acid phosphatase activity, diphosphoinositol-pentakisphosphate kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ppip5k1 itself. We selected most functions ppip5k1 had, and list some proteins which have the same functions with ppip5k1. You can find most of the proteins on our site.

    Function Related Protein
    acid phosphatase activity ACP5; PPIP5K2; MINPP1B; ACPP; PXYLP1; ACPT; ACP2; ACP5B; PAPL; ACP6
    diphosphoinositol-pentakisphosphate kinase activity PPIP5K1; PPIP5K2
    inositol hexakisphosphate 1-kinase activity IP6K3; PPIP5K2; IP6K1; IP6K2; PPIP5K1
    inositol hexakisphosphate 3-kinase activity IP6K1; PPIP5K1; IP6K2; PPIP5K2; IP6K3
    inositol hexakisphosphate 5-kinase activity IP6K3; IP6K1; PPIP5K2; PPIP5K1; IP6K2
    inositol-1,3,4,5,6-pentakisphosphate kinase activity PPIP5K1

    ppip5k1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ppip5k1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ppip5k1.

    Williams, SP; Gillaspy, GE; et al. Biosynthesis and possible functions of inositol pyrophosphates in plants. FRONTIERS IN PLANT SCIENCE 6:-(2015).
    Desai, M; Rangarajan, P; et al. Two inositol hexakisphosphate kinases drive inositol pyrophosphate synthesis in plants. PLANT JOURNAL 80:642-653(2014).

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