Recombinant Human PPIP5K1, His-tagged

• Cat.No.: PPIP5K1-13788H
• Product Overview: Recombinant Human PPIP5K1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-301a.a.
• Description: This gene encodes a dual functional inositol kinase. The encoded enzyme converts inositol hexakisphosphate to diphosphoinositol pentakisphosphate and diphosphoinositol pentakisphosphate to bis-diphosphoinositol tetrakisphosphate. This protein may be important for intracellular signaling pathways. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 15.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 [ Homo sapiens ]
• Official Symbol: PPIP5K1
• Synonyms: PPIP5K1; diphosphoinositol pentakisphosphate kinase 1; HISPPD2A, histidine acid phosphatase domain containing 2A; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1; IPS1; KIAA0377; VIP1; IP6 kinase; VIP1 homolog; insP6 and PP-IP5 kinase 1; inositol pyrophosphate synthase 1; histidine acid phosphatase domain containing 2A; histidine acid phosphatase domain-containing protein 2A; IP6K; hsVIP1; HISPPD2A; MGC51871; DKFZp313L0221
• Gene ID: 9677
• mRNA Refseq: NM_001130858
• Protein Refseq: NP_001124330
• MIM: 610979
• UniProt ID: Q6PFW1
• Chromosome Location: 15q15.3
• Pathway: inositol pyrophosphates biosynthesis, organism-specific biosystem; inositol pyrophosphates biosynthesis, conserved biosystem; superpathway of inositol phosphate compounds, organism-specific biosystem
• Function: ATP binding; acid phosphatase activity; diphosphoinositol-pentakisphosphate kinase activity; inositol hexakisphosphate 1-kinase activity; inositol hexakisphosphate 3-kinase activity; inositol hexakisphosphate 5-kinase activity; inositol-1,3,4,5,6-pentakis