PPM1K

Official Full Name

protein phosphatase, Mg2+/Mn2+ dependent, 1K
Overview

Protein phosphatase 1K, mitochondrial is an enzyme that in humans is encoded by the PPM1K gene.
Synonyms

PPM1K; protein phosphatase, Mg2+/Mn2+ dependent, 1K; protein phosphatase 1K (PP2C domain containing); protein phosphatase 1K, mitochondrial; DKFZp761G058; hPTMP; PP2C type mitochondrial phosphoprotein phosphatase; PP2Ckappa; PP2Cm; protein phosphatase 2C kappa; PP2C domain containing protein phosphatase 1K; PP2C kappa; PP2C like mitochondrial protein; Protein phosphatase 2C isoform kappa; PTMP; PP2C-kappa; PP2C-like protein; PP2C-like mitochondrial protein; PP2C type mitochondrial phosphatase; PP2C domain-containing protein phosphatase 1K; PP2C-type mitochondrial phosphoprotein phosphatase; UG0882E07;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rhesus Macaque
Zebrafish

Source

HEK293
HEK293T
Human Cell
Mammalian Cell

Tag

Flag
His
Fc
Avi
Myc
DDK
Non

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PPM1K-174H	Recombinant Human PPM1K, His-tagged	HEK293	His	Asp30-Ala372	Inquiry
Human	PPM1K-2957HCL	Recombinant Human PPM1K 293 Cell Lysate	HEK293	Non		Inquiry
Human	PPM1K-176H	Recombinant Human PPM1K Protein, DYKDDDDK-tagged	Human Cell	Flag		Inquiry
Human	PPM1K-3245H	Recombinant Human PPM1K Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc&DDK		Inquiry
Mouse	Ppm1k-5051M	Recombinant Mouse Ppm1k Protein, Myc/DDK-tagged	HEK293T	Myc&DDK		Inquiry
Rhesus Macaque	PPM1K-3555R	Recombinant Rhesus monkey PPM1K Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	PPM1K-3373R	Recombinant Rhesus Macaque PPM1K Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Rhesus Macaque	PPM1K-3373R-B	Recombinant Rhesus Macaque PPM1K Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	PPM1K-2103Z	Recombinant Zebrafish PPM1K	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

PPM1K involved in several pathways and played different roles in them. We selected most pathways PPM1K participated on our site, such as Branched-chain amino acid catabolism, Metabolism, Metabolism of amino acids and derivatives, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPM1K were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Branched-chain amino acid catabolism	HIBADHA;IVD;DLD;DBT;PPM1K;BCKDK;ALDH9A1A.2;HIBADH
Metabolism	CYP19A1;AZIN1A;OAZ2;CKB;SURF1;NOSIP;CSPG5B;MARCKSB;ACSF2
Metabolism of amino acids and derivatives	AMD2;SLC6A7;SLC6A8;PCBD1;CTHL;OAZ1A;GLS2B;OAZ2B;DAO

PPM1K has several biochemical functions, for example, metal ion binding, protein binding, protein serine/threonine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPM1K itself. We selected most functions PPM1K had, and list some proteins which have the same functions with PPM1K. You can find most of the proteins on our site.

Function	Related Protein
metal ion binding	ZFP865;ZNFX1;RPS27.2;PDE7B;CDKN1A;PVALB6;PRKCH;ZNF292A;NEK2
protein binding	KANK2;PRPF40A;HDAC1;DKK1;PDHB;YWHAZ;DAG1;USP20;ZNF16
protein serine/threonine phosphatase activity	PPM1J;UBLCP1;PPM1A;PPM1BA;PPM1F;CDC14AB;CDC14B;DULLARD;PPM1LB

PPM1K has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPM1K here. Most of them are supplied by our site. Hope this information will be useful for your research of PPM1K.

BIRC2; MYB

Research Area

Lynch, CJ; Adams, SH; et al. Branched-chain amino acids in metabolic signalling and insulin resistance. NATURE REVIEWS ENDOCRINOLOGY 10:723-736(2014).

Chan, WL; Yuo, CY; et al. Transcribed pseudogene psi PPM1K generates endogenous siRNA to suppress oncogenic cell growth in hepatocellular carcinoma. NUCLEIC ACIDS RESEARCH 41:3734-3747(2013).