Creative BioMart to Join NIH Research Festival Biotech Vendor Exhibits 2024 | Sep. 25th, 2024 Learn More

PPM1L

Official Full Name

protein phosphatase, Mg2+/Mn2+ dependent, 1L
Overview

PPM1L, or PP2CE, belongs to the PP2C group of serine/threonine phosphatases, which are distinguished from other;phosphatases by their structure, absolute requirement for Mg(2+) or Mn(2+), and insensitivity to okadaic acid. PP2Cs;regulate stress-activated protein kinase (SAPK; see MIM 601158) signaling cascades that respond to extracellular;stimuli (Jin et al., 2004 (PubMed 15560375)).
Synonyms

PPM1L; protein phosphatase, Mg2+/Mn2+ dependent, 1L; protein phosphatase 1 (formerly 2C) like; protein phosphatase 1L; PP2CE; PP2Cepsilon; Protein phosphatase 2C epsilon isoform; PP2C epsilon; protein phosphatase 2C isoform epsilon; PPM1-LIKE; PP2C-epsilo;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Bos taurus (Bovine)
Human
Mouse

Source

E.coli
E.coli expression system
HEK293
HEK293T
Mammalian Cell

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PPM1L-80H	Recombinant Human PPM1L protein, His-tagged	E.coli	His	196aa(including fusion tag)	Inquiry
Human	PPM1L-2956HCL	Recombinant Human PPM1L 293 Cell Lysate	HEK293	Non		Inquiry
Mouse	PPM1L-13204M	Recombinant Mouse PPM1L Protein	Mammalian Cell	His		Inquiry
Mouse	Ppm1l-5052M	Recombinant Mouse Ppm1l Protein, Myc/DDK-tagged	HEK293T	Myc&DDK		Inquiry
Mouse	PPM1L-6995M-B	Recombinant Mouse PPM1L Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	PPM1L-6995M	Recombinant Mouse PPM1L Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Bos taurus (Bovine)	RFL18794BF	Recombinant Full Length Bovine Protein Phosphatase 1L(Ppm1L) Protein, His-Tagged	E.coli expression system	His	Full Length (1-360)	Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

PPM1L involved in several pathways and played different roles in them. We selected most pathways PPM1L participated on our site, such as Metabolism, Metabolism of lipids and lipoproteins, Sphingolipid de novo biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPM1L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Metabolism	SULT1C2;KHK;ARSD;NDUFAF7;PFKLB;CHKA;CYP2AD3;CBLC-1;AGPAT6
Metabolism of lipids and lipoproteins	COL4A3BP;CYP11B1;SLCO1B1;SREBF2;SIN3B;DHCR24;DPEP1;PTPMT1;INSIG2
Sphingolipid de novo biosynthesis	SGMS2;SPTLC1;CERS3B;PPM1L;OSBP;PPM1LB;ACER1;CERS5;CERS4A
Sphingolipid metabolism	GLB1;ACER1;SPTLC3;SPTLC2B;CERS2A;SERINC1;NEU3.5;LASS5;ASAH1A

PPM1L has several biochemical functions, for example, metal ion binding, protein serine/threonine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPM1L itself. We selected most functions PPM1L had, and list some proteins which have the same functions with PPM1L. You can find most of the proteins on our site.

Function	Related Protein
metal ion binding	ZNF114;ZNF584;ZNF76;ZNF547;ZFP521;ZNF239;NPEPPS;PKM;ITGA2
protein serine/threonine phosphatase activity	PPM1B;MTMR4;PPEF1;CDC14AA;PPP3CA;MTMR3;PPM1LB;PPP1R3D;ILKAP

PPM1L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPM1L here. Most of them are supplied by our site. Hope this information will be useful for your research of PPM1L.