• Official Full Name

    protein phosphatase, Mg2+/Mn2+ dependent, 1L

  • Overview

    PPM1L, or PP2CE, belongs to the PP2C group of serine/threonine phosphatases, which are distinguished from other;phosphatases by their structure, absolute requirement for Mg(2+) or Mn(2+), and insensitivity to okadaic acid. PP2Cs;regulate stress-activated protein kinase (SAPK; see MIM 601158) signaling cascades that respond to extracellular;stimuli (Jin et al., 2004 (PubMed 15560375)).
  • Synonyms

    PPM1L; protein phosphatase, Mg2+/Mn2+ dependent, 1L; protein phosphatase 1 (formerly 2C) like; protein phosphatase 1L; PP2CE; PP2Cepsilon; Protein phosphatase 2C epsilon isoform; PP2C epsilon; protein phosphatase 2C isoform epsilon; PPM1-LIKE; PP2C-epsilo;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Human
  • Mouse
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PPM1L-80H Recombinant Human PPM1L protein, His-tagged E.coli His 196aa(including fusion tag)
Human PPM1L-2956HCL Recombinant Human PPM1L 293 Cell Lysate HEK293 N/A
Mouse PPM1L-13204M Recombinant Mouse PPM1L Protein Mammalian Cell His
Mouse Ppm1l-5052M Recombinant Mouse Ppm1l Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse PPM1L-6995M-B Recombinant Mouse PPM1L Protein Pre-coupled Magnetic Beads HEK293
Mouse PPM1L-6995M Recombinant Mouse PPM1L Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bos taurus (Bovine) RFL18794BF Recombinant Full Length Bovine Protein Phosphatase 1L(Ppm1L) Protein, His-Tagged E.coli expression system His Full Length (1-360)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

PPM1L involved in several pathways and played different roles in them. We selected most pathways PPM1L participated on our site, such as Metabolism, Metabolism of lipids and lipoproteins, Sphingolipid de novo biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPM1L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Metabolism of lipids and lipoproteinsLBR;MED23;PITPNB;ABHD3;PEMT;ABHD4;MED8;ARF3;SLC44A5B
Sphingolipid de novo biosynthesisGDF1;ACER1;CERS5;PPM1L;SGMS2;COL4A3BP;PPM1LB;CERS3B;CERS4A

PPM1L has several biochemical functions, for example, metal ion binding, protein serine/threonine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPM1L itself. We selected most functions PPM1L had, and list some proteins which have the same functions with PPM1L. You can find most of the proteins on our site.

Function Related Protein
metal ion bindingCYP2K18;ATP1A1A.3;HBAA1;ZFP239;ZNF823;DGKE;ACY3.2;DNAJA1;PRICKLE1B
protein serine/threonine phosphatase activityILKAP;PPP6C;DUSP23;UBLCP1;PPM1L;PPM1DA;TAB1;PPM1K;CTDNEP1A

PPM1L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPM1L here. Most of them are supplied by our site. Hope this information will be useful for your research of PPM1L.

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