primpol
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Official Full Name
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PRIMPOL-3506Z | Recombinant Zebrafish PRIMPOL | Mammalian Cells | Zebrafish | His |
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| PRIMPOL-5235H | Recombinant Human PRIMPOL Protein, GST-tagged | Wheat Germ | Human | GST |
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| PRIMPOL-7789HCL | Recombinant Human CCDC111 293 Cell Lysate | HEK293 | Human | Non |
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| PRIMPOL-3894HF | Recombinant Full Length Human PRIMPOL Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 560 amino acids |
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Involved Pathway
primpol involved in several pathways and played different roles in them. We selected most pathways primpol participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with primpol were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
primpol has several biochemical functions, for example, DNA primase activity,DNA-directed DNA polymerase activity,chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by primpol itself. We selected most functions primpol had, and list some proteins which have the same functions with primpol. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| manganese ion binding | MRE11A,DCP2,XPNPEP3,XPNPEP1,PPEF1,LAP3,TDP2B,GALNT2,ARG1,LARGE |
| chromatin binding | NEUROD1,PRKAA2,AJUBA,EWSR1A,SIRT2,MEOX1,RCC1,TBL1Y,NOC2L,SATB1 |
| DNA-directed DNA polymerase activity | MYBBP1A,CCDC111,POLD3,CHRAC1,POLG,POLB,POLD4,POLN,POLL,POLK |
| DNA primase activity | CCDC111,CTU1,PRIM1,UAP1L1,PRIM2 |
| protein binding | EID1,THAP7,ECM1,ARMCX1,CANX,PAWR,ORC3L,PRAM1,RPL28,KLRC4-KLRK1 |
Interacting Protein
primpol has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with primpol here. Most of them are supplied by our site. Hope this information will be useful for your research of primpol.
RPA1;RPA2;RPA3;RFWD3;TIPIN;CLSPN;SMARCAL1;TIMELESS
Resources
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References
- Keen, BA; Bailey, LJ; et al. Human PrimPol mutation associated with high myopia has a DNA replication defect. NUCLEIC ACIDS RESEARCH 42:12102-12111(2014).
- Guilliam, TA; Jozwiakowski, SK; et al. Human PrimPol is a highly error-prone polymerase regulated by single-stranded DNA binding proteins. NUCLEIC ACIDS RESEARCH 43:1056-1068(2015).
