PRKAR2A involved in several pathways and played different roles in them. We selected most pathways PRKAR2A participated on our site, such as Apoptosis, Insulin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRKAR2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| Apoptosis |
IL1B; PPP3CB; HIST1H1E; BID; MAP3K14; BIDA; PRKACBB; IRF2; NFKB1; HMGB2A |
| Insulin signaling pathway |
EIF4E2RS1; FLOT1; PRKCI; IKBKB; PRKAB1; CALM; AKT3A; FLOT2; SOCS1A; PRKAG2 |
PRKAR2A has several biochemical functions, for example, cAMP binding, cAMP-dependent protein kinase inhibitor activity, cAMP-dependent protein kinase regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRKAR2A itself. We selected most functions PRKAR2A had, and list some proteins which have the same functions with PRKAR2A. You can find most of the proteins on our site.
| Function |
Related Protein |
| cAMP binding |
PRKAR1B; PRKAR2B; CNGA2; RAPGEF4; PDE11A; CNGA4; POPDC2; PDE2A; RAPGEF3; HCN4 |
| cAMP-dependent protein kinase inhibitor activity |
PKIB; PRKAR1A; PKIA; PRKAR1B; PRKAR2B; PKIG; PRKAR2A; PRKAG2 |
| cAMP-dependent protein kinase regulator activity |
PRKAG2; PRKAG1; PRKAR1A; PRKAR2B; PRKAR1AA; PRKAR2AA; PRKAR2AB; PRKAR1B; PRKAR1AB; PRKAR2A |
| protein binding |
CIB4; NSFL1C; RNF24; USP19; UBAC1; CLEC4G; AMPH; JUB; KCNRG; CARD8 |
| protein kinase A catalytic subunit binding |
PJA2; SOX9; RYR2; GSK3B; PRKAR2B; PRKAR1A; PKIA; KCNQ1; CSK; PRKAR2A |
| ubiquitin protein ligase binding |
GRIK2; STUB1; TRAF6; ABI2; CUL4B; GABARAP; RNF34; TRAF4; SMAD6; MFN2 |
PRKAR2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRKAR2A here. Most of them are supplied by our site. Hope this information will be useful for your research of PRKAR2A.
AKAP1; p03259-2; 3',5'-cyclic amp; PRKACA; AKAP5; AKAP3; 8-aha-camp
Han, YS; Arroyo, J; et al. Human heart failure is accompanied by altered protein kinase A subunit expression and post-translational state. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 538:25-33(2013).
Kronberg, F; Giacometti, R; et al. Characterization of the regulatory subunit of Yarrowia lipolytica cAMP-dependent protein kinase. Evidences of a monomeric protein. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 509:66-75(2011).
