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PRKX

  • Official Full Name

    protein kinase, X-linked

  • Overview

    This gene encodes a serine threonine protein kinase that has similarity to the catalytic subunit of cyclic AMP dependent protein kinases. The encoded protein is developmentally regulated and may be involved in renal epithelial morphogenesis. This protein may also be involved in macrophage and granulocyte maturation. Abnormal recombination between this gene and a related pseudogene on chromosome Y is a frequent cause of sex reversal disorder in XX males and XY females. Pseudogenes of this gene are found on chromosomes X, 15 and Y.
  • Synonyms

    PRKX; protein kinase, X-linked; cAMP-dependent protein kinase catalytic subunit PRKX; PKX1; protein kinase X; protein kinase PKX1; protein kinase X-linked; serine/threonine-protein kinase PRKX;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Insect (sf21)
  • Insect Cell
  • Mammalian Cell
  • Sf21
  • Sf9 Insect Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PRKX-163HFL Active Recombinant Full Length Human PRKX Protein, N-His-tagged Sf21 His Full Length
Human PRKX-1090H Recombinant Human Protein Kinase, X-Linked, GST-tagged Sf9 Insect Cell GST
Human PRKX-1963H Recombinant Human PRKX, GST-tagged E.coli GST 1-358aa
Human PRKX-30107TH Recombinant Human PRKX Wheat Germ N/A 90 amino acids
Human PRKX-2845HCL Recombinant Human PRKX 293 Cell Lysate HEK293 N/A
Human PRKX-1101H Recombinant Human PRKX Protein (M1-F358), GST tagged Insect Cell GST M1-F358
Human PRKX-2072HF Active Recombinant Full Length Human PRKX Protein, GST-tagged Insect (sf21) GST 1-358
Human PRKX-749H Recombinant Human PRKX Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PRKX-1100H Recombinant Human PRKX Protein (M1-F358), Tag Free Insect Cell No tag M1-F358
Mouse PRKX-13381M Recombinant Mouse PRKX Protein Mammalian Cell His
Mouse PRKX-7104M Recombinant Mouse PRKX Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse PRKX-7104M-B Recombinant Mouse PRKX Protein Pre-coupled Magnetic Beads HEK293
Mouse Prkx-5129M Recombinant Mouse Prkx Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat Prkx-722R Recombinant Rat Prkx Protein, His-tagged E.coli His Trp49~Phe358
Rhesus Macaque PRKX-3610R Recombinant Rhesus monkey PRKX Protein, His-tagged Mammalian Cell His
Rhesus Macaque PRKX-3428R Recombinant Rhesus Macaque PRKX Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque PRKX-3428R-B Recombinant Rhesus Macaque PRKX Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PRKX Related Articles

PRKX involved in several pathways and played different roles in them. We selected most pathways PRKX participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PRKX were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

PRKX has several biochemical functions, for example, ATP binding, cAMP-dependent protein kinase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PRKX itself. We selected most functions PRKX had, and list some proteins which have the same functions with PRKX. You can find most of the proteins on our site.

Function Related Protein
ATP bindingGM711;CDK2;NLRP3;ACSBG2;DCLK3;CCT4;ATP1A3A;HSPA5;NAIP6
cAMP-dependent protein kinase activityPRKACB;PRKACG;PRKACA;PRKAA1;AKAP13;PRKX;PRKAG1
protein bindingVGLL2;FAM131C;ADM;C1orf187;TP73;MRPL28;SRSF5;CHMP4C;DDX41

PRKX has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRKX here. Most of them are supplied by our site. Hope this information will be useful for your research of PRKX.

SMAD6; HSP90AB1; PRKAR1A; GPKOW; N/A; Prkacb

Bender, C; Ullrich, A; et al. PRKX, TTBK2 and RSK4 expression causes sunitinib resistance in kidney carcinoma- and melanoma-cell lines. INTERNATIONAL JOURNAL OF CANCER 131:E45-E55(2012).
Li, W; Yu, ZX; et al. Profiles of PrKX expression in developmental mouse embryo and human tissues. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 53:1003-1009(2005).
MARINO, IR; CELLI, S; et al. ANTIBODY-BINDING TO ENDOTHELIAL AND EPITHELIAL ANTIGENS TRIGGERS PIG-TO-RABBIT XENOGRAFT REJECTION AND ITS ABSENCE RESULTS IN ATYPICAL COMPLEMENT DEPOSITION. TRANSPLANT INTERNATIONAL 5:S320-S322(1992).
  • Q&As
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