PRMT8

  • Official Full Name

    protein arginine methyltransferase 8

  • Overview

    Arginine methylation is a widespread posttranslational modification mediated by arginine methyltransferases, such as PRMT8. Arginine methylation is involved in a number of cellular processes, including DNA repair, RNA transcription, signal transduction, protein compartmentalization, and possibly protein translation (Lee et al., 2005 [PubMed 16051612]).[supplied by OMIM, Mar 2008]
  • Synonyms

    PRMT8; protein arginine methyltransferase 8; HRMT1L3; HRMT1L4; protein arginine N-methyltransferase 8; HMT1 hnRNP methyltransferase-like 3; protein arginine N-methyltransferase 4; heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PRMT8-180H Recombinant Human PRMT8 Protein, His-tagged E.coli His 61-394
Human PRMT8-5043H Recombinant Human PRMT8 Protein, GST-tagged Wheat Germ GST
Human PRMT8-2837HCL Recombinant Human PRMT8 293 Cell Lysate HEK293 N/A
Human PRMT8-126H Recombinant Human PRMT8 Protein, GST-tagged E.coli GST
Human PRMT8-004H Recombinant Human PRMT8 Protein, GST-tagged E.coli GST
Mouse PRMT8-13422M Recombinant Mouse PRMT8 Protein Mammalian Cell His
Mouse PRMT8-7128M Recombinant Mouse PRMT8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse PRMT8-7128M-B Recombinant Mouse PRMT8 Protein Pre-coupled Magnetic Beads HEK293
Mouse Prmt8-5136M Recombinant Mouse Prmt8 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Kit-1862 PRMT8 Chemiluminescent Assay Kit N/A
Kit-1863 PRMT8 Homogeneous Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PRMT8 involved in several pathways and played different roles in them. We selected most pathways PRMT8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PRMT8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

PRMT8 has several biochemical functions, for example, S-adenosylmethionine-dependent methyltransferase activity, histone methyltransferase activity (H4-R3 specific), histone-arginine N-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRMT8 itself. We selected most functions PRMT8 had, and list some proteins which have the same functions with PRMT8. You can find most of the proteins on our site.

Function Related Protein
S-adenosylmethionine-dependent methyltransferase activityLCMT1;ASMT2;PRMT7;LSM1;MEPCE;RRP8;TPMT.1;PRMT8;AS3MT
histone methyltransferase activity (H4-R3 specific)PRMT6;PRMT1;PRMT8B;PRMT8;PRMT7
histone-arginine N-methyltransferase activityCARM1;PRMT8;PRMT7;PRMT3;PRMT5;PRMT2;PRMT6
identical protein bindingACADM;SH3BP4;PKD2;ALCAMA;PIK3AP1;POU3F2;MIEF1;USP15;CEACAM5
protein bindingTAG-260;NME1;TMEM27;VMP1;FAM58A;KCNH7;OPRM1;JAM3B;SERINC1
protein heterodimerization activityENO3;H2AFX;ATF4;HOMER2;CD3D;PRMT5;HIF1A;DMRT3;HIST1H2BP
protein homodimerization activityNLRC4;APOBEC3G;P2RX7;TYW5;TCF4;GSTM3;RCHY1;CHMP1A;BST2
protein-arginine omega-N asymmetric methyltransferase activityCARM1;PRMT2;PRMT1;PRMT6;PRMT7;PRMT3;PRMT8B;PRMT8
protein-arginine omega-N monomethyltransferase activityPRMT8B;PRMT7;PRMT8;PRMT6

PRMT8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRMT8 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRMT8.

SYNCRIP; PRMT1; COIL; VHL; PPARA; DCAF8; CEP162; OFCC1; SERBP1; GPATCH2L; ZNF451

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