• Official Full Name

    protein arginine methyltransferase 8

  • Background

    Arginine methylation is a widespread posttranslational modification mediated by arginine methyltransferases, such as PRMT8. Arginine methylation is involved in a number of cellular processes, including DNA repair, RNA transcription, signal transduction, protein compartmentalization, and possibly protein translation (Lee et al., 2005 [PubMed 16051612]).[supplied by OMIM, Mar 2008]
  • Synonyms

    PRMT8; protein arginine methyltransferase 8; HRMT1L3; HRMT1L4; protein arginine N-methyltransferase 8; HMT1 hnRNP methyltransferase-like 3; protein arginine N-methyltransferase 4; heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4;
    • Type:
    • Assay Kits
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Human
    • Mouse
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • His (Fc)
    • Avi
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Kit-1863 PRMT8 Homogeneous Assay Kit N/A
    Kit-1862 PRMT8 Chemiluminescent Assay Kit N/A
    Human PRMT8-126H Recombinant Human PRMT8 Protein, GST-tagged E. coli GST
    Human PRMT8-2837HCL Recombinant Human PRMT8 293 Cell Lysate HEK293 N/A
    Human PRMT8-004H Recombinant Human PRMT8 Protein, GST-tagged E.coli GST
    Human PRMT8-5043H Recombinant Human PRMT8 Protein, GST-tagged Wheat Germ GST
    Human PRMT8-180H Recombinant Human PRMT8 Protein, His-tagged E.coli His
    Mouse PRMT8-13422M Recombinant Mouse PRMT8 Protein Mammalian Cell His
    Mouse PRMT8-7128M Recombinant Mouse PRMT8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse PRMT8-7128M-B Recombinant Mouse PRMT8 Protein Pre-coupled Magnetic Beads HEK293
    Mouse Prmt8-5136M Recombinant Mouse Prmt8 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    • Involved Pathway
    • Protein Function
    • Interacting Protein

    PRMT8 involved in several pathways and played different roles in them. We selected most pathways PRMT8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PRMT8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    PRMT8 has several biochemical functions, for example, S-adenosylmethionine-dependent methyltransferase activity, histone methyltransferase activity (H4-R3 specific), histone-arginine N-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRMT8 itself. We selected most functions PRMT8 had, and list some proteins which have the same functions with PRMT8. You can find most of the proteins on our site.

    Function Related Protein
    S-adenosylmethionine-dependent methyltransferase activityMETTL7A;PRMT7;RRP8;MEPCE;ASMT2;TPMT.2;SUV39H1;LSM1;COQ5
    histone methyltransferase activity (H4-R3 specific)PRMT8;PRMT1;PRMT6;PRMT7;PRMT8B
    histone-arginine N-methyltransferase activityPRMT3;CARM1;PRMT8;PRMT6;PRMT5;PRMT7;PRMT2
    identical protein bindingRAF1;GOT2A;DIAPH1;WRNIP1;NDC80;DRG1;GCC2;TARDBP;CLDN11
    protein bindingATP1A1;GYPB;ZFPM2A;COX6B2;EPN3;RUNDC3A;RIBC2;TBC1D20;C14orf104
    protein heterodimerization activitySDCBP;ADIPOR2;SNX5;DRAP1;SRI;APOA2;CAV2;BNIP3;BNIP3L
    protein homodimerization activityMAOB;CSF1R;NTRK1;UGT1A6A;PRLR;GRIK1;TARS;RBM44;NLGN4X
    protein-arginine omega-N asymmetric methyltransferase activityPRMT7;CARM1;PRMT8;PRMT6;PRMT1;PRMT2;PRMT8B;PRMT3
    protein-arginine omega-N monomethyltransferase activityPRMT6;PRMT8;PRMT8B;PRMT7

    PRMT8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRMT8 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRMT8.


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