prmt8 Protein, protein arginine methyltransferase 8

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prmt8

Official Full Name	protein arginine methyltransferase 8
Background	Arginine methylation is a widespread posttranslational modification mediated by arginine methyltransferases, such as PRMT8. Arginine methylation is involved in a number of cellular processes, including DNA repair, RNA transcription, signal transduction, protein compartmentalization, and possibly protein translation (Lee et al., 2005 [PubMed 16051612]).[supplied by OMIM, Mar 2008]
Synonyms	PRMT8; protein arginine methyltransferase 8; HRMT1L3; HRMT1L4; protein arginine N-methyltransferase 8; HMT1 hnRNP methyltransferase-like 3; protein arginine N-methyltransferase 4; heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4;

Species :
Human
Mouse

Source :
E.coli
HEK293
HEK293T
Mammalian Cell
Wheat Germ

Tag :
GST
His
Myc/DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag
Human	PRMT8-004H	Recombinant Human PRMT8 Protein, GST-tagged	E.coli	GST
Mouse	Prmt8-5136M	Recombinant Mouse Prmt8 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK
Human	PRMT8-180H	Recombinant Human PRMT8 Protein, His-tagged	E.coli	His
Human	PRMT8-2837HCL	Recombinant Human PRMT8 293 Cell Lysate	HEK293	N/A
Human	PRMT8-5043H	Recombinant Human PRMT8 Protein, GST-tagged	Wheat Germ	GST
Mouse	PRMT8-13422M	Recombinant Mouse PRMT8 Protein	Mammalian Cell	His
	Kit-1862	PRMT8 Chemiluminescent Assay Kit		N/A
	Kit-1863	PRMT8 Homogeneous Assay Kit		N/A

Involved Pathway Protein Function Interacting Protein

prmt8 involved in several pathways and played different roles in them. We selected most pathways prmt8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with prmt8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

prmt8 has several biochemical functions, for example, S-adenosylmethionine-dependent methyltransferase activity, histone methyltransferase activity (H4-R3 specific), histone-arginine N-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by prmt8 itself. We selected most functions prmt8 had, and list some proteins which have the same functions with prmt8. You can find most of the proteins on our site.

Function	Related Protein
S-adenosylmethionine-dependent methyltransferase activity	TPMT.1; LSM1; AS3MT; ASMT2; LCMT1; C6orf211; SUV39H1; PRMT8; WBSCR27; PRMT7
histone methyltransferase activity (H4-R3 specific)	PRMT8B; PRMT6; PRMT8; PRMT1; PRMT7
histone-arginine N-methyltransferase activity	PRMT7; PRMT3; PRMT8; CARM1; PRMT5; PRMT2; PRMT6
identical protein binding	CBY1; SRPX2; KCTD17; INHBA; ERN1; CTSC; BNIPL; TRP63; LRRK1; USP15
protein binding	MRAS; PRPF4B; LRRC4B; PSMB1; DST; SFTPD; HIST1H4G; SKA3; TOR1AIP2; DLL1
protein heterodimerization activity	NPM1; POLA1; VAPA; UBXN6; HIST1H2AC; TPD52L1; BNIP3L; TERF1; JDP2; PVALB
protein homodimerization activity	CPOX; G6PD; DAXX; FGFR1OP2; LRRK2; ENG; MTUS2; SLC30A8; MAP3K5; DMRTA2
protein-arginine omega-N asymmetric methyltransferase activity	PRMT1; PRMT3; CARM1; PRMT8; PRMT8B; PRMT6; PRMT7; PRMT2
protein-arginine omega-N monomethyltransferase activity	PRMT6; PRMT8; PRMT8B; PRMT7

prmt8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with prmt8 here. Most of them are supplied by our site. Hope this information will be useful for your research of prmt8.

SYNCRIP; PRMT1; COIL; VHL; PPARA; DCAF8; CEP162; OFCC1; SERBP1; GPATCH2L; ZNF451

prmt8

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prmt8

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