PTBP2
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Official Full Name
polypyrimidine tract binding protein 2 -
Overview
The protein encoded by this gene binds to the intronic cluster of RNA regulatory elements, downstream control sequence (DCS). It is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein but it is expressed primarily in the brain. -
Synonyms
PTBP2;polypyrimidine tract binding protein 2;polypyrimidine tract-binding protein 2;brPTB;nPTB;PTB;PTBLP;PTB-like protein;splicing regulator;neurally-enriched homolog of PTB;neural polypyrimidine tract binding protein;neural polypyrimidine trac
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PTBP2-83H | Recombinant Human PTBP2 protein, His-tagged | E.coli | Human | His | 546aa(including fusion tag) |
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| PTBP2-83HFL | Recombinant Human PTBP2 protein, Full Length, N-His tagged | E.coli | Human | His | Full L. Full Length | |
| PTBP2-13621M | Recombinant Mouse PTBP2 Protein | Mammalian Cells | Mouse | His |
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| PTBP2-4796R | Recombinant Rat PTBP2 Protein | Mammalian Cells | Rat | His |
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| PTBP2-2727HCL | Recombinant Human PTBP2 293 Cell Lysate | HEK293 | Human | Non |
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| PTBP2-4455R | Recombinant Rat PTBP2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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| PTBP2-4455R-B | Recombinant Rat PTBP2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| PTBP2-7240M | Recombinant Mouse PTBP2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| PTBP2-7240M-B | Recombinant Mouse PTBP2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PTBP2 involved in several pathways and played different roles in them. We selected most pathways PTBP2 participated on our site, such as mRNA processing, which may be useful for your reference. Also, other proteins which involved in the same pathway with PTBP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| mRNA processing | MCTS2,TXNL4A,PTBP1,LSMD1,VPRBP,DHX15,SPOP,RBM12B2,DHX8,ZFP346 |
Protein Function
PTBP2 has several biochemical functions, for example, mRNA binding,nucleotide binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PTBP2 itself. We selected most functions PTBP2 had, and list some proteins which have the same functions with PTBP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | RALYL,FCF1,RG9MTD1,SRSF1,HMGB2,STAU1,SRSF9,BST2,YTHDF3,ZC3HAV1 |
| nucleotide binding | PTBP2B,RAB11BB,RNPS1,SGK2B,WNK2,P2RX4A,HSC70,NONO,ARL4AA,HSP90AA1 |
| mRNA binding | KIAA0020,CELF3,CSTF2T,SNRPC,ZFP36L1,RPS2,NCBP2,RPL35,QK,MRPS7 |
Interacting Protein
PTBP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTBP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PTBP2.
RBM10;QKI;TOM1;KHDRBS3;HNRNPC;SNRPA;MATR3;PCBP3;KHDRBS1;GOLGA2;CALCOCO2;HNRNPD;ELAVL1;HNRNPAB;RBM4;EIF5A2;PUF60
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