"PTBP2" Related Products

Recombinant Human PTBP2 protein, His-tagged

Cat.No.: PTBP2-83H
Product Overview: Recombinant Human PTBP2, fused with N-His tag, was expressed in E. coli.
Description: RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. Beside its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA.
Source: E.coli
Species: Human
Tag: His
Form: 20mM Tris.Cl, 50mM NaCl, 50% Glycerol, pH8.0.
Molecular Mass: 59.4kDa(including fusion tag)
Protein length: 546aa(including fusion tag)
Applications: WB, ELISA, IP, antibody production, protein array
Storage: Store at -80centigrade and avoid repeated freeze-thaw cycles
Gene Name: PTBP2 polypyrimidine tract binding protein 2 [ Homo sapiens ]
Official Symbol: PTBP2
Synonyms: PTBP2; polypyrimidine tract binding protein 2; polypyrimidine tract-binding protein 2; brPTB; nPTB; PTB; PTBLP; PTB-like protein; splicing regulator; neurally-enriched homolog of PTB; neural polypyrimidine tract binding protein; neural polypyrimidine tract-binding protein; nPTB5; nPTB6; nPTB7; nPTB8; FLJ34897;
Gene ID: 58155
mRNA Refseq: NM_021190
Protein Refseq: NP_067013
MIM: 608449
UniProt ID: Q9UKA9
Chromosome Location: 1p21.3
Pathway: mRNA processing, organism-specific biosystem;
Function: mRNA binding; nucleotide binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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