ptgdr2 Protein, prostaglandin D2 receptor 2


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Official Full Name prostaglandin D2 receptor 2
Background This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3 UTR of this gene have been associated with asthma susceptibility.
Synonyms PTGDR2; prostaglandin D2 receptor 2; G protein coupled receptor 44 , GPR44; putative G-protein coupled receptor 44; CD294; chemoattractant receptor homologous molecule expressed on T helper type 2 cells; CRTH2; DP2; CD294 antigen; Chemoattractant receptor homologous molecule expressed on Th2 cells; Chemoattractant receptor-homologous molecule expressed on Th2 cells; CRTH 2; DL1R; G Protein Coupled Receptor 44; GPR 44; Gpr44; GPR44_HUMAN; Putative G protein coupled receptor 44; G protein-coupled receptor 44
    • Species :
    • Rat
    • Source :
    • Mammalian Cell
    • Tag :
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Rat PTGDR2-4803R Recombinant Rat PTGDR2 Protein Mammalian Cell His

    ptgdr2 involved in several pathways and played different roles in them. We selected most pathways ptgdr2 participated on our site, such as Class A/1 (Rhodopsin-like receptors), Eicosanoid ligand-binding receptors, G alpha (i) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with ptgdr2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Class A/1 (Rhodopsin-like receptors) AMCF-II; TAC2; PTGDR2; NTS; TAC3; GPR37L1; ADRB1; ADRA2A; HEBP1; NPSR1
    Eicosanoid ligand-binding receptors OXER1; PTGDR2; CYSLTR1; GPR17; LTB4R
    G alpha (i) signalling events RGS4; S1PR3; RGS18; CCR1; APLN; SSTR4; SST1.1; LPAR5A; POMCB; HEBP1
    GPCR downstream signaling MCF2L; OXGR1; ADORA3; CCR1; SCT; HCAR1-2; PYY; NPFFR2; ARHGAP4; LPAR1
    GPCR ligand binding NMB; OPN4A; RLN3A; RGR; RXFP2; GAL; ADRA2B; CCK; RAMP3; S1PR1
    GPCRs, Class A Rhodopsin-like SSTR4; NMUR1; HRH3; GPR65; GPR31; GPR6; ADORA1; CCR7; OPN1LW; FPR-RS4
    Prostanoid ligand receptors PTGDR2
    Signal Transduction CIT; NOG1; ADM2; GPR31; TAX1BP1B; SPOPL; GPR55A; INSL3; RGS1; RHOJ

    ptgdr2 has several biochemical functions, for example, G-protein coupled receptor activity, neuropeptide binding, prostaglandin D receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ptgdr2 itself. We selected most functions ptgdr2 had, and list some proteins which have the same functions with ptgdr2. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor activity MTNR1BB; OR5K1; APLNR; OR8K5; TAAR14L; GPR98; GPR97; COR1; GPR182; TAS2R104
    neuropeptide binding NPY8AR; GPR1; OPRD1; OPRM1; SSTR1; MC4R; OPRL1; SSTR2; SSTR4; MRGPRB1
    prostaglandin D receptor activity PTGDR2; PTGDR
    prostaglandin F receptor activity PTGFR; PTGDR2; PTGER1C
    prostaglandin J receptor activity PTGDR; PTGDR2

    ptgdr2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ptgdr2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ptgdr2.

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