QRFPR

  • Official Full Name

    pyroglutamylated RFamide peptide receptor
  • Overview

    Pyroglutamylated RFamide peptide receptor also known as orexigenic neuropeptide QRFP receptor or G-protein coupled receptor 103 (GPR103) is a protein that in humans is encoded by the QRFPR gene.
  • Synonyms

    QRFPR;pyroglutamylated RFamide peptide receptor;G protein coupled receptor 103 , GPR103;QRFP receptor;G protein-coupled receptor 103;G-protein coupled receptor 103;orexigenic neuropeptide QRFP receptor;AQ27;GPR103;SP9155;MGC149217

Recombinant Proteins

  • Human
  • Mouse
  • Chicken
  • Rat
  • Mus musculus
  • E.coli
  • Mammalian Cells
  • HEK293
  • His
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
QRFPR-2093H Recombinant Human QRFPR, His-tagged E.coli Human His 303-431aa
QRFPR-13766M Recombinant Mouse QRFPR Protein Mammalian Cells Mouse His
QRFPR-3837C Recombinant Chicken QRFPR Mammalian Cells Chicken His
QRFPR-4866R Recombinant Rat QRFPR Protein Mammalian Cells Rat His
QRFPR-4525R Recombinant Rat QRFPR Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
QRFPR-4525R-B Recombinant Rat QRFPR Protein Pre-coupled Magnetic Beads HEK293 Rat
QRFPR-7326M Recombinant Mouse QRFPR Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
QRFPR-7326M-B Recombinant Mouse QRFPR Protein Pre-coupled Magnetic Beads HEK293 Mouse
RFL12695HF Recombinant Full Length Human Pyroglutamylated Rfamide Peptide Receptor(Qrfpr) Protein, His-Tagged E.coli Human His Full L. Full Length (1-431)
RFL23796RF Recombinant Full Length Rat Pyroglutamylated Rfamide Peptide Receptor(Qrfpr) Protein, His-Tagged E.coli Rat His Full L. Full Length (1-433)
RFL8297MF Recombinant Full Length Mouse Pyroglutamylated Rfamide Peptide Receptor(Qrfpr) Protein, His-Tagged E.coli Mus musculus His Full L. Full Length (1-433)

    Involved Pathway

    QRFPR involved in several pathways and played different roles in them. We selected most pathways QRFPR participated on our site, such as Class A/1 (Rhodopsin-like receptors),G alpha (q) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with QRFPR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Signal Transduction KREMEN2,TAC2,DSCAMA,GPR120,NOG1,RGS20,BCO2,FGD4A,GHRB,RDH14B
    G alpha (q) signalling events CHRM1,GPR17,TAC3,NMU,OPN4,APPA,HCRT,GRP,FFAR3,LPAR2B
    Gastrin-CREB signalling pathway via PKC and MAPK GPR65,NTS,TRPC3,MGLL,OPN4.1,FPR-RS6,NPS,PROK2,NMBB,LPAR2A
    Peptide ligand-binding receptors NMS,NMB,TAC2,TAC1,NMBA,GPR37B,ZFPM2B,CXCR7B,GAL,PROKR2
    GPCR downstream signaling PROKR1,GNA13,CCL35.1,PTHLHA,UTS2,OPN1LW1,PNOCB,ADCYAP1B,PTGDR2,TAC3
    Orexin and neuropeptides FF and QRFP bind to their respective receptors QRFP,NPFFR2,HCRT,NPFF
    Class A/1 (Rhodopsin-like receptors) ADRB2,OXGR1A.2,RLN2,ADRA2B,ADORA2A,GPR18,GPR31B,AGT,EDNRAB,GPR55A
    GPCR ligand binding PENK,OPN4.1,OPN1LW,NPB,AMCF-II,RLN3A,OPN1SW,ADM2A,ADORA1,S1PR1

    Protein Function

    QRFPR has several biochemical functions, for example, G-protein coupled receptor activity,neuropeptide Y receptor activity,peptide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by QRFPR itself. We selected most functions QRFPR had, and list some proteins which have the same functions with QRFPR. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor activity OR8B8,Fzd4,GHRHR2,CCR1L1,OLFR493,VMN2R26,TACR1B,GPR146,OLFR495,OR51D1
    peptide binding GNRHR4,NPFFR2.1,CRHBP,LTA4H,PCSK5,AVPR1B,ERCC3,H2-Q10,CTSL2,CRIP1
    neuropeptide Y receptor activity PROKR1,NPY1R,PRLHR2B,PRLHR,NPY8AR,NPY8BR,PRLHR2A,PRLH2R,NPY5R,PROKR2

    Interacting Protein

    QRFPR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with QRFPR here. Most of them are supplied by our site. Hope this information will be useful for your research of QRFPR.

    Resources

    References

    • Primeaux, SD; et al. QRFP in female rats: Effects on high fat food intake and hypothalamic gene expression across the estrous cycle. PEPTIDES 32:1270-1275(2011).
    • Fukusumi, S; Fujii, R; et al. Recent advances in mammalian RFamide peptides: The discovery and functional analyses of PrRP, RFRPs and QRFP. PEPTIDES 27:1073-1086(2006).
    • Fukusumi, S; Yoshida, H; et al. A new peptidic ligand and its receptor regulating adrenal function in rats. JOURNAL OF BIOLOGICAL CHEMISTRY 278:46387-46395(2003).
    • Patel, SR; Murphy, KG; et al. Pyroglutamylated RFamide peptide 43 stimulates the hypothalamic-pituitary-gonadal axis via gonadotropin-releasing hormone in rats. ENDOCRINOLOGY 149:4747-4754(2008).

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