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Official Full Name RAD17 homolog
Background The human checkpoint protein Rad17 and its fission and budding yeast orthologues (Schizosaccharomyces pombe Rad17 and Saccharomyces cerevisiae Rad24, respectively) are involved in the activation of checkpoint signals in response to DNA damage or disruptio
Synonyms RAD17; RAD17 homolog (S. pombe); RAD1 (S. pombe) homolog; cell cycle checkpoint protein RAD17; CCYC; RAD17Sp; Rad24; RAD1 homolog; Rad17-like protein; RF-C activator 1 homolog; RF-C/activator 1 homolog; cell cycle checkpoint protein (RAD17); R24L
    • Species :
    • Chicken
    • Human
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human RAD17-2152H Recombinant Human RAD17, GST-tagged E.coli GST
    Human RAD17-2153H Recombinant Human RAD17 Protein, His-tagged E.coli His
    Human RAD17-2562HCL Recombinant Human RAD17 293 Cell Lysate HEK293 N/A
    Human RAD17-2563HCL Recombinant Human RAD17 293 Cell Lysate HEK293 N/A
    Chicken RAD17-7137C Recombinant Chicken RAD17 Mammalian Cell His
    Zebrafish RAD17-771Z Recombinant Zebrafish RAD17 Mammalian Cell His

    rad17 involved in several pathways and played different roles in them. We selected most pathways rad17 participated on our site, such as Activation of ATR in response to replication stress, Cell Cycle, Cell Cycle Checkpoints, which may be useful for your reference. Also, other proteins which involved in the same pathway with rad17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Activation of ATR in response to replication stress DBF4; MCM10; CDK2; MCM8; RAD1; RAD9; RAD9A; RAD9B; HUS1; RAD17
    Cell Cycle NEK7; BLZF1; RAD50; RAD17; CUL1; STIL; ORC4; CEP72; ABL1; YWHAH
    Cell Cycle Checkpoints CHEK2; BABAM1; KAT5; BRCC3; RAD9; YWHAQ; HUS1; MCM8; RAD9A; RAD17
    DNA Double-Strand Break Repair KDM4B; KIAA0146; HUS1; TDP2B; RAD17; POLD3; PARP2; TDP1; BABAM1; HTATIP
    DNA Repair YY1; KDM4B; EME2; PPP4R2B; UBE2L6; DDB1; EYA4; USP43A; TDP2B; CETN2
    DNA damage response RAD9A; GADD45G; DDB2; CDK5; HUS1B; GADD45A; RAD1; RAD17; TLK2; CHEK2
    G2/M Checkpoints RAD1; HUS1; BABAM1; TP53BP1; RAD9; RAD17; UIMC1; BARD1; RAD9B; RAD9A
    Gastric cancer network 2 CHTF8; PLAC8; S100A6; LBR; CEBPZ; MTDH; RNF144B; TOP2A; ATAD2; SNURF

    rad17 has several biochemical functions, for example, ATP binding, DNA clamp loader activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by rad17 itself. We selected most functions rad17 had, and list some proteins which have the same functions with rad17. You can find most of the proteins on our site.

    Function Related Protein
    DNA clamp loader activity RFC3; RAD17
    protein binding RIPK2; LHX4; FPR1; HCFC1; TXNDC12; SDC2; FNIP1; C6orf226; GPM6A; RYK

    rad17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with rad17 here. Most of them are supplied by our site. Hope this information will be useful for your research of rad17.

    NBN; MRE11A; RAD50; RAD9A; FZR1; USP20; PRMT6; npm_alk; CBX6; CBX7

    Sukhanova, MV; D'Herin, C; et al. Interaction of Ddc1 and RPA with single-stranded/double-stranded DNA junctions in yeast whole cell extracts: Proteolytic degradation of the large subunit of replication protein A in ddc1 Delta strains. DNA REPAIR 22:30-40(2014).
    Young, JL; Koon, EC; et al. Differential hRad17 expression by histologic subtype of ovarian cancer. JOURNAL OF OVARIAN RESEARCH 4:-(2011).

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