rad23a

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rad23a

Official Full Name RAD23 homolog A
Background The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
Synonyms RAD23A; RAD23 homolog A (S. cerevisiae); RAD23 (S. cerevisiae) homolog A; UV excision repair protein RAD23 homolog A; HHR23A; MGC111083; RAD23; yeast homolog; A; HR23A; RAD23, yeast homolog, A
    • Species :
    • Human
    • Source :
    • E.coli
    • HEK293
    • Yeast
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human RAD23A-1499H Recombinant Human RAD23A Protein (1-363 aa), His-tagged Yeast His
    Human RAD23A-2153H Recombinant Human RAD23A, GST-tagged E.coli GST
    Human RAD23A-2559HCL Recombinant Human RAD23A 293 Cell Lysate HEK293 N/A

    rad23a involved in several pathways and played different roles in them. We selected most pathways rad23a participated on our site, such as Nucleotide excision repair, Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with rad23a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Nucleotide excision repair NFRKB; MCRS1; ZFP830; ERCC4; CCNH; ERCC3; BIVM-ERCC5; XPA; ERCC2; PCNA
    Protein processing in endoplasmic reticulum UBE2D3; UBE2D2L; FBXO2; CAPN1B; UBE2E2; MBTPS1; PDIP5; DNAJC10; CRYAB; BAX

    rad23a has several biochemical functions, for example, damaged DNA binding, polyubiquitin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by rad23a itself. We selected most functions rad23a had, and list some proteins which have the same functions with rad23a. You can find most of the proteins on our site.

    Function Related Protein
    damaged DNA binding FANCG; TP53BP1; POLK; HMGB2; FEN1; CREBBP; RPA3; XRCC1; POLB; XRCC5
    polyubiquitin binding BAG6; UBQLN1; HDAC6; THRSP; PSMD4B; UBXN1; SHARPIN; FAM175A; BRCC3; ZFAND6
    protein binding CUL1; MRPL40; GTF2F1; RBM42; TXLNB; LETMD1; MT1A; PCDH18; AKAP7; KCNMA1
    single-stranded DNA binding IGHMBP2; RPA4; HNRNPDL; BRCA2; RPA3; LUZP4; BLM; CSDA; MCM10; XPC
    ubiquitin-specific protease binding SART3; CHMP3; BAG6; PARK7; SYVN1; VCP; RAD23A; SELS; VPS24; AMFR

    rad23a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with rad23a here. Most of them are supplied by our site. Hope this information will be useful for your research of rad23a.

    PSMD4; TRAF2; TRAF5; TRIP6; ANKRD40; ZBTB44

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