Recombinant Full Length Human RAD23A Protein, C-Flag-tagged

• Cat.No.: RAD23A-1924HFL
• Product Overview: Recombinant Full Length Human RAD23A Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair. Proteins in this family have a modular domain structure consisting of an ubiquitin-like domain (UbL), ubiquitin-associated domain 1 (UbA1), XPC-binding domain and UbA2. The protein encoded by this gene plays an important role in nucleotide excision repair and also in delivery of polyubiquitinated proteins to the proteasome. Alternative splicing results in multiple transcript variants encoding multiple isoforms.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 39.4 kDa
• AA Sequence: MAVTITLKTLQQQTFKIRMEPDETV KVLKEKIEAEKGRDAFPVAGQKLIY AGKILSDDVPIRDYRIDEKN FVVVMVTKTKAGQGTSAPPEASPTA APESSTSFPPAPTSGMSHPPPAARE DKSPSEESAPATSPESVSGS VPSSGSSGREEDAASTLVTGSEYET MLTEIMSMGYERERVVAALRASYNN PHRAVEYLLTGIPGSPEPEH GSVQESQVSEQPATEAGENPLEFLR DQPQFQNMRQVIQQNPALLPALLQQ LGQENPQLLQQISRHQEQFI QMLNEPPGELADISDVEGEVGAIGE EAPQMNYIQVTPQEKEAIERLKALG FPESLVIQAYFACEKNENLA ANFLLSQNFDDE TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome
• Protein Pathways: Nucleotide excision repair

Gene Information

• Gene Name: RAD23A RAD23 homolog A, nucleotide excision repair protein [ Homo sapiens (human) ]
• Official Symbol: RAD23A
• Synonyms: HR23A; HHR23A
• Gene ID: 5886
• mRNA Refseq: NM_005053.4
• Protein Refseq: NP_005044.1
• MIM: 600061
• UniProt ID: P54725