Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

RAD51B

  • Official Full Name

    RAD51 paralog B

  • Overview

    The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Jul 2011]
  • Synonyms

    RAD51B; RAD51 paralog B; REC2; R51H2; RAD51L1; DNA repair protein RAD51 homolog 2; RAD51 homolog B; RecA-like protein; recombination repair protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • N/A
  • N
  • T7|His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RAD51B-2465H Recombinant human RAD51B, His-tagged E.coli His
Human RAD51B-121H Recombinant Human RAD51B protein, T7/His-tagged E.coli T7/His
Human RAD51L1-2157H Recombinant Human RAD51L1 protein, His-tagged E.coli His 1-384aa
Human RAD51B-2554HCL Recombinant Human RAD51L1 293 Cell Lysate HEK293 N/A
Mouse Rad51b-6781M Recombinant Mouse Rad51b Protein (Met121-Pro350), N-His tagged E.coli N-His Met121-Pro350
Zebrafish RAD51B-12585Z Recombinant Zebrafish RAD51B Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • RAD51B Related Articles

RAD51B involved in several pathways and played different roles in them. We selected most pathways RAD51B participated on our site, such as Homologous recombination, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAD51B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Homologous recombinationRPA3;RAD51C;XRCC2;RAD51D;CDK5R2;MRE11A;RAD52;MUS81;SYCP3

RAD51B has several biochemical functions, for example, ATP binding, DNA binding, DNA-dependent ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RAD51B itself. We selected most functions RAD51B had, and list some proteins which have the same functions with RAD51B. You can find most of the proteins on our site.

Function Related Protein
ATP bindingPRKCZ;PDK4;MAP3K2;SMC3;CKMB;CHTF18;HUNK;SPG7;TGFBR1
DNA bindingPOU3F1;FOXD1L;IRX5B;BARHL1B;ZFP1;TOP1;HOXB1A;ZNF521;YY1
DNA-dependent ATPase activityMSH5;SMARCAL1;MSH2;DHX36;RAD51L1;CHD6;ERCC6;TOP2A;MSH3
double-stranded DNA bindingDDX11;MRE11A;PYDC3;ERCC5;PIN4;FBXO18;LSM14A;MTERFD1;FEN1
contributes_to endodeoxyribonuclease activityDMC1;RAD51L1;RAD51D;RAD51;RAD51B;ERCC4;XRCC2;RAD51L3
contributes_to four-way junction DNA bindingMSH2;XRCC3;RAD51B;RAD51D;XRCC2;RAD51L1;RAD51C;RAD51L3;MSH6
protein bindingRMND5A;UBE4A;RHOJ;CRIPAK;FBXO3;C16orf5;DDX39A;ZFPM2A;POLM
recombinase activityRAD51L1;XRCC3;RAD51D;XRCC2;RAD51C;RBPJ;RAD51B;RAD51;DMC1
single-stranded DNA bindingLONP1;C10orf2;SSBP2;BRCA2;RAD51D;HNRNPK;HNRPDL;TTC6;FUBP1

RAD51B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAD51B here. Most of them are supplied by our site. Hope this information will be useful for your research of RAD51B.

Kim, K; Bang, SY; et al. High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci. ANNALS OF THE RHEUMATIC DISEASES 74:-(2015).
McAllister, K; Yarwood, A; et al. Identification of BACH2 and RAD51B as Rheumatoid Arthritis Susceptibility Loci in a Meta-Analysis of Genome-Wide Data. ARTHRITIS AND RHEUMATISM 65:3058-3062(2013).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All RAD51B Products

Required fields are marked with *

My Review for All RAD51B Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends