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Official Full Name RAD51 homolog C
Background This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be;involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two;other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein;in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair.;This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast;tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor;progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have;been identified.
Synonyms RAD51C; RAD51 homolog C (S. cerevisiae); RAD51 (S. cerevisiae) homolog C; DNA repair protein RAD51 homolog 3; RAD51L2; R51H3; RAD51-like protein 2; yeast RAD51 homolog 3; RAD51 homolog C, isoform 1; FANCO; BROVCA3; MGC104277
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human RAD51C-2555HCL Recombinant Human RAD51C 293 Cell Lysate HEK293 N/A
    Human RAD51C-28601TH Recombinant Human RAD51C Wheat Germ N/A
    Human RAD51C-680H Recombinant Human RAD51C Protein, His-tagged E.coli His
    Mouse RAD51C-13872M Recombinant Mouse RAD51C Protein Mammalian Cell His
    Zebrafish RAD51C-1607Z Recombinant Zebrafish RAD51C Mammalian Cell His

    rad51c involved in several pathways and played different roles in them. We selected most pathways rad51c participated on our site, such as Homologous recombination, Fanconi anemia pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with rad51c were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Homologous recombination POLD2; RAD51; SHFM1; XRCC2; BLM; TOP3A; EME1; BRCA2; RPA3; NBN
    Fanconi anemia pathway FANCC; TELO2; REV1; FANCD2; FAN1; BRCA2; DCLRE1A; FUZ; C19orf40; POLH

    rad51c has several biochemical functions, for example, ATP binding, DNA binding, DNA-dependent ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by rad51c itself. We selected most functions rad51c had, and list some proteins which have the same functions with rad51c. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding SIX7; RFX2; TBX2A; CERS5; HIST1H3G; PHC3; ZNF621; HMGXB4; ESRRGA; SOX19A
    DNA-dependent ATPase activity CDK7; RAD51B; TTF2; XRCC2; DHX36; SMARCAL1; SMARCA4; ERCC6; MSH4; RAD51L3
    contributes_to crossover junction endodeoxyribonuclease activity SLX4; RAD51C; XRCC3
    double-stranded DNA binding HNRNPDL; DMC1; USF1; MTERF3; KLF6; FEV; RAD51L1; PYDC3; MEN1; TRP63
    contributes_to four-way junction DNA binding MSH6; RAD51L3; RAD51L1; XRCC2; MSH2; RAD51C; XRCC3; RAD51D; RAD51B
    protein binding ARFIP2; CTDSP2; PRKD3; ZNF131; CWC15; CRADD; GTF2F2; FNIP1; GSN; AKR7A3
    recombinase activity XRCC3; XRCC2; DMC1; RAD51B; RAD51D; RBPJ; RAD51L3; RAD51L1; RAD51; RAD51C
    single-stranded DNA binding CDAN1; LUZP4; IGHMBP2; RAD51L1; HNRNPK; PURA; YBX1; SSBP1; ANXA1; SETMAR

    rad51c has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with rad51c here. Most of them are supplied by our site. Hope this information will be useful for your research of rad51c.

    XRCC3; RAD51B; RAD51D

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