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RAD54L

Official Full Name

RAD54-like (S. cerevisiae)
Overview

The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.
Synonyms

RAD54L; RAD54-like (S. cerevisiae); RAD54 (S.cerevisiae) like; DNA repair and recombination protein RAD54-like; hHR54; hRAD54; RAD54A; RAD54 homolog; HR54;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

HEK293
HEK293T
Mammalian Cell
Mammalian cells

Tag

C
Myc
DDK
Flag
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	RAD54L-2552HCL	Recombinant Human RAD54L 293 Cell Lysate	HEK293	N/A	Inquiry
Human	RAD54L-1853H	Recombinant Human RAD54L Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Human	RAD54L-1549HFL	Recombinant Full Length Human RAD54L Protein, C-Flag-tagged	Mammalian cells	Flag	Inquiry
Human	RAD54L-5042H	Recombinant Human RAD54L Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK	Inquiry
Human	RAD54L-390H	Recombinant Human RAD54L Protein, MYC/DDK-tagged, C13 and N15-labeled	HEK293	C-Myc/DDK	Inquiry
Human	RAD54L-1853H-B	Recombinant Human RAD54L Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	Rad54l-5352M	Recombinant Mouse Rad54l Protein, Myc/DDK-tagged	HEK293T	Myc/DDK	Inquiry
Zebrafish	RAD54L-11363Z	Recombinant Zebrafish RAD54L	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein

RAD54L involved in several pathways and played different roles in them. We selected most pathways RAD54L participated on our site, such as Homologous recombination, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAD54L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Homologous recombination	CDK5R2;RAD52;POLD2;FUZ;RAD51L3;RAD54B;RPA3;RAD54L;BRCA2

RAD54L has several biochemical functions, for example, ATP binding, DNA binding, annealing helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RAD54L itself. We selected most functions RAD54L had, and list some proteins which have the same functions with RAD54L. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	GM7168;EIF4A2;KIF3B;PRKG2;ATP2A2A;UPF1;STRADA;THRAP3;CLK4
DNA binding	PRRX1B;HNF1BB;NR4A3;H2AFVA;LIN28B;HIST1H4E;PRM2;ALX3;ZSCAN1
annealing helicase activity	SMARCAL1;RECQL4;RAD54L;RECQL;ANXA1;ZRANB3;BLM
helicase activity	DHX34;DICER1;HELLS;WRN;CHD6;SMARCA4;MCM6L;ACTG2;MOV10
protein binding	SLC1A1;KIF18A;PPP2R3C;UTP14A;FOXJ2;THAP11;MAD1L1;AHCYL2;SNRNP40

RAD54L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAD54L here. Most of them are supplied by our site. Hope this information will be useful for your research of RAD54L.

TNKS2; WDYHV1; NCK1; BAG6; LIMK1; Tecpr2; SGTB