RBCK1
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Official Full Name
RanBP-type and C3HC4-type zinc finger containing 1 -
Overview
The protein encoded by this gene is similar to mouse UIP28/UbcM4 interacting protein. Alternative splicing has been observed at this locus, resulting in distinct isoforms. -
Synonyms
RBCK1;RanBP-type and C3HC4-type zinc finger containing 1;C20orf18, chromosome 20 open reading frame 18;ranBP-type and C3HC4-type zinc finger-containing protein 1;RBCK2;RNF54;UBCE7IP3;XAP4;ZRANB4;RING finger protein 54;HBV associated factor 4;H
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Zebrafish
- Rat
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- Myc
- Avi
- Fc
- DDK
Involved Pathway
RBCK1 involved in several pathways and played different roles in them. We selected most pathways RBCK1 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with RBCK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of TNFR1 signaling | OTUD7B,SHARPIN,CLIP3,SHRPRBCK1R,FAM105B,TAX1BP1B,TAX1BP1,RNF31,USP2,OTULINB |
| TNF signaling | TAX1BP1B,FAM105B,USP4,CLIP3,SHARPIN,OTULINB,RNF31,USP2,OTUD7B,SHRPRBCK1R |
| Proteasome degradation | STUB1,TRIM11,DZIP3,UBE2J2,IWS1,RNF220,UBR2,NPEPPS,UBE2U,KLHL21 |
| Adaptive Immune System | OSBPL1A,CD207,AKT3,CD200,IGKV1-5,FRS2,ARIH2,CTSK,RASGRP2,ACTR1B |
| presentation | UBE2E3,FBXO44,LRR1,RNF111,RNF41,RNF14,LRSAM1,SPSB2,ASB2,UBR1 |
| Signal Transduction | RHOV,GDI1,ROPN1,OR10A5,GNA13B,HECW1,OMG,RSPO2,SKIA,CLPS |
| Antigen processing: Ubiquitination & | RNF182,NPEPPS,SPSB2,RNF14,LTN1,RNF41,LRRC41,WSB1,FBXO44,KLHL21 |
| Class I MHC mediated antigen processing & | ASB11,ASB6,PJA1,ASB3,SEC61B,CMTM2A,UFL1,LRSAM1,UBE2E3,ASB8 |
| Death Receptor Signalling | CYLD,USP4,TAB1,OTULINB,SHRPRBCK1R,TAX1BP1,SHARPIN,RNF31,GNB2L1,USP2 |
Protein Function
RBCK1 has several biochemical functions, for example, ligase activity,protein binding,NOT transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RBCK1 itself. We selected most functions RBCK1 had, and list some proteins which have the same functions with RBCK1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ubiquitin-protein transferase activity | UBE2O,FBXL7,HECTD3,MIB2,MUL1B,TRAF4B,RNF220,RNF139,BRCA1,PRP19 |
| ligase activity | ACSF2,DTX2,MARCH6,CNOT4,MARCH5,TRIM13,UBE2D1B,PIAS3,RNF212,GLULC |
| protein binding | ERCC6L,ATG7,SEC23A,DPY30,STK38,CBY1,DGCR8,ASB9,SIX5,Tnfrsf22 |
| NOT transcription factor activity, sequence-specific DNA binding | EDF1,DMRTB1 |
| zinc ion binding | TRIM15,PHC3,BMI1,PHF20B,BTR16,IFIH1,SHRPRBCK1R,KLF4,LONRF3,ZFAND5A |
| ubiquitin binding | PARK2,UBXN11,NBR1,UBE2N,TOM1L1,BRAP,DNAJC2,DYRK2,OTUB1A,USP25 |
Interacting Protein
RBCK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RBCK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RBCK1.
RNF31
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