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RC3H1

Official Full Name

ring finger and CCCH-type domains 1
Overview

RC3H1, or roquin, encodes a highly conserved member of the RING type ubiquitin ligase protein family (Vinuesa et al.,;2005 (PubMed 15917799)). The roquin protein is distinguished by the presence of a CCCH zinc finger found in;RNA-binding proteins, and localization to cytosolic RNA granules implicated in regulating mRNA translation and;stability.
Synonyms

RC3H1; ring finger and CCCH-type domains 1; ring finger and CCCH type zinc finger domains 1; roquin; KIAA2025; KIAA2025 protein; RNF198; RP5 1198E17.5; RING finger protein 198; RING finger and C3H zinc finger protein 1; ring finger and CCCH-type zinc fing;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	RC3H1-714H	Recombinant Human RC3H1 Protein, MYC/DDK-tagged	HEK293	Myc/DDK	Inquiry
Human	RC3H1-624H	Recombinant Human RC3H1 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK	Inquiry
Mouse	Rc3h1-5432M	Recombinant Mouse Rc3h1 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK	Inquiry
Zebrafish	RC3H1-5251Z	Recombinant Zebrafish RC3H1	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein

RC3H1 involved in several pathways and played different roles in them. We selected most pathways RC3H1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RC3H1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

RC3H1 has several biochemical functions, for example, metal ion binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RC3H1 itself. We selected most functions RC3H1 had, and list some proteins which have the same functions with RC3H1. You can find most of the proteins on our site.

Function	Related Protein
metal ion binding	TANK;PRDM6;ZNFL2A;PAK3;ACY3.2;SP8;TYRP1B;MBTD1;EYA4
zinc ion binding	NR4A1;RAG2;SUV39H1A;CYHR1;PEX2;ZFAND2A;NR1D4B;PML;DZIP3

RC3H1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RC3H1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RC3H1.